393-42-0Relevant articles and documents
Facile synthesis and biological evaluation of novel fluorine-containing N-nitro-N′-substituted phenylurea
Wang, Yunchun,Bai, Zhongyuan,Wei, Zengjun,Xu, Shengzhen,Li, Xuegang,Li, Jianhong,Cao, Xiufang,Chen, Changshui
experimental part, p. 1029 - 1039 (2012/04/17)
Twenty-two novel N-nitro-N′-substituted phenyl-N-(2,6-dibromo-4- fluorophenyl)urea derivatives were designed and synthesized via a simple and convenient BTC 'one-pot' procedure using DMAP as the catalyst. The structures of all newly synthesized compounds were confirmed by IR, 1H NMR, and elemental analysis, and a part has been identified by 13C NMR. The preliminary bioassay indicates that the target compounds possesses moderate herbicidal activity against Sorghum sudanense. However, some of the title compounds presented high plant growth regulating activity against rape.
Zur Synthese sulfonierter Derivate von 4-Fluoranilin
Courtin, Alfred
, p. 546 - 550 (2007/10/02)
Syntheses of Sulfonated Derivatives of 4-Fluoroaniline; Synthesis of 2-amino-5-fluorobenzenesulfonic acid (2) was achieved by baking the hydrogen sulfate of 4-fluoroaniline (1).Sulfonation of p-fluoroacetanilide (4) with oleum followed by hydrolysis gave 5-amino-2-fluorobenzenesulfonic acid (3).The same reaction with 1 yielded 3 in an impure state.The structures of 2 and 3 were confirmed by converting the diazonium chlorides derived from 5-fluoro-2-nitroaniline (5) and from 2-fluoro-5-nitroaniline (8) to 5-fluoro-2-nitrobenzenesulfonyl chloride (6) and 2-fluoro-5-nitrobenzenesulfonyl chloride (9), respectively, followed by hydrolysis of 6 to 5-fluoro-2-nitrobenzenesulfonic acid (7), and of 9 to 2-fluoro-5-nitrobenzenesulfonic acid (10), and by final reduction.Compound 10 was also obtained by sulfonation of 1-fluoro-4-nitrobenzene (11) with oleum.