393129-62-9Relevant academic research and scientific papers
Pyridazine derivatives and related compounds. Part 11: 1Synthesis of some pyrimido[4′,5′:4,5]thieno[2,3-c] pyridazines
Deeb, Ali,Kotb, Mahmoud,El-Abbasy, Mohamed
, p. 2245 - 2252 (2004)
3-Substituted pyrimido[4′,5′:4,5]thieno[2,3-c/pyridazine-2,4- di-ones and 3-amino-2-methylpyrimido[4′,5′:4,5]thieno[2,3-c] pyridazine-4-ones were synthesized starting from ethyl 5-aminothieno[2,3-c] pyridazine-6-carboxylate 1. Reaction of amino ester 1 with phenyl isothiocyanate affords thiourea derivative 10 which undergo further transformation to the related fused heterocyclic systems.
