393570-60-0Relevant academic research and scientific papers
Antiprotozoal activity and DNA binding of dicationic acridones
Montalvo-Quirós, Sandra,Taladriz-Sender, Andrea,Kaiser, Marcel,Dardonville, Christophe
, p. 1940 - 1949 (2015)
Dicationic acridone derivatives were synthesized and their antiparasitic activity was evaluated. Acridones displayed in vitro nanomolar IC50 values against Trypanosoma brucei rhodesiense STIB900 with selectivity indices >1000. Compounds 1b, 3a,
Therapeutic acridone and acridine compounds
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Page/Page column 46; sheet 3, (2008/06/13)
The present invention pertains to acridone and acridine compounds of formula (I), wherein either: (a) K is ═O, L is —H, alpha is a single bond, beta is a double bond, gamma is a single bond (acridones); or, (b) K is a 9-substituent, L is absent, alpha is
