52156-62-4

Upstream product

• 40703-09-1 2,6-dinitro-10H-acridin-9-one 
• 857549-95-2 4-acetylamino-2-(3-amino-anilino)-benzoic acid 
• 857550-00-6 4-acetylamino-2-(4-acetylamino-anilino)-benzoic acid 
• 2516-96-3 2-chloro-5-nitrobenzoic acid 
• 99-60-5 2-chloro-4-nitrobenzoic acid 
• 89-54-3 2-chloro-5-aminobenzoic acid 
• 1744-92-9 3-nitro-9,10-dihydroacridin-9-one 
• 1744-91-8 9-chloro-3-nitroacridine 
• 49551-01-1 2-anilino-4-nitrobenzoic acid 
• 62-53-3 aniline 
• 122-80-5 N-acetyl-p-phenylenediamine 
• 20983-73-7 N-(4-nitrophenyl)-4-nitroanthranilic acid 
• 100-01-6 4-nitro-aniline 
• 108-45-2 m-phenylenediamine 

Downstream Products

• 3407-94-1 2,6-diamino-acridine 

Relevant academic research and scientific papers

Antiprotozoal activity and DNA binding of dicationic acridones

Dicationic acridone derivatives were synthesized and their antiparasitic activity was evaluated. Acridones displayed in vitro nanomolar IC50 values against Trypanosoma brucei rhodesiense STIB900 with selectivity indices >1000. Compounds 1b, 3a,

Therapeutic acridone and acridine compounds

The present invention pertains to acridone and acridine compounds of formula (I), wherein either: (a) K is ═O, L is —H, alpha is a single bond, beta is a double bond, gamma is a single bond (acridones); or, (b) K is a 9-substituent, L is absent, alpha is