3939-23-9

Basic information

• Product Name: 3-bromo-10H-phenothiazine
• Synonyms: 3-bromo-10H-phenothiazine;10H-Phenothiazine, 3-bromo-
• CAS NO: 3939-23-9
• Molecular Formula: C₁₂H₈BrNS
• Molecular Weight: 278.16762
• Mol File: 3939-23-9.mol
• Article Data: 11

Chemical Properties

• Melting Point: 181.5 °C
• Boiling Point: 410.5°Cat760mmHg
• Flash Point: 202.1°C
• Appearance: /
• Density: 1.564g/cm³
• Vapor Pressure: 5.99E-07mmHg at 25°C
• Refractive Index: 1.695
• Storage Temp.: 2-8°C(protect from light)
• PKA: -1.87±0.20(Predicted)
• CAS DataBase Reference: 3-bromo-10H-phenothiazine(CAS DataBase Reference)
• NIST Chemistry Reference: 3-bromo-10H-phenothiazine(3939-23-9)
• EPA Substance Registry System: 3-bromo-10H-phenothiazine(3939-23-9)

Safety Data

• Hazardous Substances Data: 3939-23-9(Hazardous Substances Data)

Usage

General Description

3-bromo-10H-phenothiazine is a chemical compound with the molecular formula C12H8BrN. It belongs to the phenothiazine class of organic compounds, which are often used in the pharmaceutical industry for their various biological activities. The presence of the bromine atom in the molecule gives it unique properties and potential applications in organic synthesis and drug discovery. It is known for its anti-inflammatory and anti-parasitic properties and is being studied for its potential use in the treatment of certain diseases. Additionally, 3-bromo-10H-phenothiazine has been found to exhibit antibacterial and antitumor activities, making it a promising candidate for further research in the field of medicinal chemistry.

InChI:InChI=1/C12H8BrNS/c13-8-5-6-10-12(7-8)15-11-4-2-1-3-9(11)14-10/h1-7,14H

Upstream product

• 92-84-2 10H-phenothiazine 
• 3460-18-2 1,4-dibromo-2-nitrobenzene 
• 137-07-5 2-amino-benzenethiol 
• 6320-03-2 2-chlorothiphenol 
• 562080-91-5 N-(4-bromo-2-iodophenyl)acetamide 
• 6320-02-1 o-bromothiophenol 

Downstream Products

• 68230-59-1 10H-phenothiazine-3-carboxylic acid 
• 1160637-73-9 3-((E)-2-(pyridin-4-yl)vinyl)-10H-phenothiazine 
• 1256379-26-6 3-((E)-(4-methoxystyryl))-10H-phenothiazine 
• 1256379-23-3 3-((E)-(4-acetoxystyryl))-10H-phenothiazine 
• 1256379-27-7 3-((E)-2-(phenol-4-yl)vinyl)-10H-phenothiazine 
• 1256379-25-5 3-((E)-(4-aminostyryl))-10H-phenothiazine 

Relevant articles and documents

Thiophene-forming one-pot synthesis of three thienyl-bridged oligophenothiazines and their electronic properties

The pseudo five-component Sonogashira-Glaser cyclization synthesis of symmetrically 2,5-diaryl-substituted thiophenes is excellently suited to access thienyl-bridged oligophenothiazines in a one-pot fashion. Three thienyl-bridged systems were intensively studied by UV-vis and fluorescence spectroscopy as well as by cyclic voltammetry. The oxidation proceeds with lower oxidation potentials and consistently reversible oxidations can be identified. The Stokes shifts are large and substantial fluorescence quantum yields can be measured. Computational chemistry indicates lowest energy conformers with sigmoidal and helical structure, similar to oligophenothiazines. TD-DFT and even semiempirical ZINDO calculations reproduce the trends of longest wavelengths absorption bands and allow the assignment of these transitions to possess largely charge-transfer character from the adjacent phenothiazinyl moieties to the central thienyl unit.

HETEROAROMATIC DERIVATIVE COMPOUND FOR ORGANIC ELECTROLUMINESCENT DEVICE AND ORGANIC ELECTROLUMINESCENT DEVICE COMPRISING THE SAME

A compound for an organic electroluminescent device comprises the compound 1. It is thereby possible. The present invention relates to a heterocyclic compound for an organic electroluminescent device and a method for manufacturing the same. Structural 1.

ANTI-INFECTIVE HETEROCYCLIC COMPOUNDS AND USES THEREOF

The present invention relates to heterocyclic compounds of Formula I useful as anti-infective agents. The present invention further relates to a method of treating an infection by administering such compounds, and to pharmaceutical compositions comprising such compounds.