394729-98-7 Usage
Uses
Used in Pharmaceutical Industry:
2-Chloro-4-Methoxy-3-pyridinecarboxylic acid is used as a pharmaceutical intermediate for the synthesis of various drugs, such as antimalarial and antifungal agents. Its unique chemical structure allows it to serve as a key building block in the development of new medications with improved efficacy and safety profiles.
Used in Antimalarial Drug Development:
2-Chloro-4-Methoxy-3-pyridinecarboxylic acid is used as a key component in the development of antimalarial drugs. Its chemical properties enable it to target and inhibit the growth of Plasmodium parasites, which are responsible for causing malaria. 2-Chloro-4-Methoxy-3-pyridinecarboxylic acid has the potential to contribute to the creation of more effective treatments for this life-threatening disease.
Used in Antifungal Drug Development:
In addition to its antimalarial applications, 2-Chloro-4-Methoxy-3-pyridinecarboxylic acid is also utilized in the development of antifungal drugs. Its ability to interfere with the growth and reproduction of various fungi makes it a valuable asset in the fight against fungal infections, which can be challenging to treat with existing medications.
Used in Research and Development:
2-Chloro-4-Methoxy-3-pyridinecarboxylic acid is used in research and development for exploring its potential therapeutic applications in treating various diseases and conditions. Its unique chemical properties and versatility in drug synthesis make it an attractive candidate for further investigation and development of novel therapeutic agents.
Check Digit Verification of cas no
The CAS Registry Mumber 394729-98-7 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 3,9,4,7,2 and 9 respectively; the second part has 2 digits, 9 and 8 respectively.
Calculate Digit Verification of CAS Registry Number 394729-98:
(8*3)+(7*9)+(6*4)+(5*7)+(4*2)+(3*9)+(2*9)+(1*8)=207
207 % 10 = 7
So 394729-98-7 is a valid CAS Registry Number.
394729-98-7Relevant academic research and scientific papers
PYRROLIDINE OREXIN RECEPTOR ANTAGONISTS
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, (2016/07/05)
The present invention is directed to pyrrolidine compounds which are antagonists of orexin receptors. The present invention is also directed to uses of the compounds described herein in the potential treatment or prevention of neurological and psychiatric disorders and diseases in which orexin receptors are involved. The present invention is also directed to compositions comprising these compounds. The present invention is also directed to uses of these compositions in the potential prevention or treatment of such diseases in which orexin receptors are involved.
COMPOUNDS AND METHODS OF USE
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Page/Page column 111, (2010/11/27)
Selected compounds are effective for prophylaxis and treatment of diseases, such as angiogenesis mediated diseases. The invention encompasses novel compounds, analogs, prodrugs and pharmaceutically acceptable salts thereof, pharmaceutical compositions and methods for prophylaxis and treatment of diseases and other maladies or conditions involving, cancer and the like. The subject invention also relates to processes for making such compounds as well as to intermediates useful in such processes.
Concise total syntheses of variolin B and deoxyvariolin B
Anderson, Regan J.,Hill, Jonathan B.,Morris, Jonathan C.
, p. 6204 - 6212 (2007/10/03)
The total synthesis of the marine alkaloid variolin B has been achieved in 8 steps and 17% overall yield, starting from commercially available 4-chloro-2-methylthiopyrimidine. The key reaction involves the tandem deoxygenation and cyclization of a triarylmethanol using a combination of triethylsilane and trifluoroacetic acid. In addition, the deoxygenated analogue was prepared in 6 steps and 23% overall yield, starting from the same starting material.
