39478-05-2Relevant academic research and scientific papers
Direct C-H Arylation of Heteroarenes with Copper Impregnated on Magnetite as a Reusable Catalyst: Evidence for CuO Nanoparticle Catalysis in Solution
Vásquez-Céspedes, Suhelen,Chepiga, Kathryn M.,M?ller, Nadja,Sch?fer, Andreas H.,Glorius, Frank
, p. 5954 - 5961 (2016/09/09)
A reusable copper-based catalyst system was employed for the direct arylation of electron-rich heteroarenes. Under mild and operationally simple reaction conditions good yields and selectivities were obtained using diaryliodonium salts as coupling partners. A combination of experimental methods including kinetic studies, filtration tests, and a series of analytical tools (TXRF, ICP-MS, SEM, XPS, TEM, EFTEM) provide evidence for catalytically active soluble nanoparticles formed from an amorphous heterogeneous precursor. Mechanistic studies hint at a redox-neutral process which promotes counterion dissociation from the diaryliodonium salt by a copper(II) oxide species.
Nickel-NHC-catalyzed cross-coupling of 2-methylsulfanylbenzofurans with alkyl grignard reagents
Baralle, Alexandre,Otsuka, Shinya,Guérin, Vincent,Murakami, Kei,Yorimitsu, Hideki,Osuka, Atsuhiro
supporting information, (2015/02/19)
NiCl2(PPh3)(IPr) catalyzes cross-coupling reactions of 2-methylsulfanylbenzofurans with alkyl Grignard reagents. Other nickel complexes such as NiCl2(dppe) failed to catalyze the same reaction. The alkylation is applicable to the synthesis of a couple of protein tyrosine phosphatase inhibitors, 3-(4-biphenylyl)-2-alkylbenzofurans.
