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Dibenzo[b,d]furan-3-ylboronic acid is an organic compound with the chemical structure consisting of a dibenzofuran core with a boronic acid functional group attached. It is a versatile building block in organic synthesis and holds potential applications in the pharmaceutical industry due to its unique chemical properties.

395087-89-5

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395087-89-5 Usage

Uses

Used in Organic Synthesis:
Dibenzo[b,d]furan-3-ylboronic acid is used as an intermediate in organic synthesis for the creation of various complex organic molecules. Its boronic acid group allows for versatile reactions, such as Suzuki-Miyaura cross-coupling, which is widely utilized in the formation of carbon-carbon bonds.
Used in Pharmaceutical Industry:
In the pharmaceutical industry, dibenzo[b,d]furan-3-ylboronic acid serves as a key intermediate in the development of new drugs. Its unique structure can be incorporated into drug candidates to modulate their biological activity, potentially leading to the discovery of novel therapeutic agents.
Used in Laboratory Research and Development:
Dibenzo[b,d]furan-3-ylboronic acid is also utilized in laboratory research and development settings. Researchers employ dibenzo[b,d]furan-3-ylboronic acid to explore new reaction pathways, develop innovative synthetic methods, and study its reactivity with various other molecules.
Used in Chemical and Pharmaceutical Production Processes:
Finally, dibenzo[b,d]furan-3-ylboronic acid is employed in the production processes of the chemical and pharmaceutical industries. Its incorporation into manufacturing processes can lead to the efficient synthesis of target compounds, ultimately contributing to the development of new products and advancements in these sectors.

Synthesis

In a 300 ml three-necked flask, 7.2 g of 4-bromodibenzofuran was dissolved in ?78° C. anhydrous tetrahydrofuran (THF) under an argon atmosphere. Then, 20 ml of an n-butyl lithium-n-hexane solution (1.6 M, 1.1 eq) was added and stirred for 1 hour. 4.23 ml (1.3 eq) of trimethoxyborane (B(OMe)3) was added and stirred for 2 hours, and the temperature of the reaction system was increased to room temperature. 200 ml of 1 N hydrochloric acid was added into the reactant and stirred for 3 hours. An organic layer was separated, and solvents were distilled off. In the crude product thus obtained, hexane was added. Precipitated product was filtered to obtain 4.94 g of dibenzofuran-4-boronic acid as a white solid (yield 80percent). The product was measured by FAB-MS, and dibenzofuran-4-boronic acid having a molecular weight of 212 was detected.

Check Digit Verification of cas no

The CAS Registry Mumber 395087-89-5 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 3,9,5,0,8 and 7 respectively; the second part has 2 digits, 8 and 9 respectively.
Calculate Digit Verification of CAS Registry Number 395087-89:
(8*3)+(7*9)+(6*5)+(5*0)+(4*8)+(3*7)+(2*8)+(1*9)=195
195 % 10 = 5
So 395087-89-5 is a valid CAS Registry Number.

395087-89-5Relevant academic research and scientific papers

COMPOUND, MATERIAL FOR ORGANIC ELECTROLUMINESCENCE ELEMENT, ORGANIC ELECTROLUMINESCENCE ELEMENT, AND ELECTRONIC DEVICE

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Paragraph 0305; 0309, (2020/02/10)

A novel compound represented by formula (1): wherein R1 to R7, R11 to R18, L1 to L3, a to c, n, and Ar are as defined in the description, provides an organic electroluminescence device having a device lifetime further improved.

NOVEL TRIAZINE COMPOUND, AND ORGANIC ELECTRONIC ELEMENT AND PLANT-GROWING LIGHTING THAT USE THE SAME

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, (2018/07/28)

PROBLEM TO BE SOLVED: To provide a triazine compound which has a high triplet energy level and excellent heat resistance, and can be used as an organic electronic element material realizing an element with high efficiency, low voltage and a long life. SOLUTION: In the triazine compound, as represented by the general formula [1] in the figure, a triazine backbone moiety is linked to a dibenzofuran or dibenzothiophene backbone moiety via a biphenyl backbone moiety, where X is an oxygen atom or sulfur atom. SELECTED DRAWING: None COPYRIGHT: (C)2018,JPO&INPIT

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