39544-81-5Relevant articles and documents
Ligand-Free CuI-Catalyzed Chemoselective S-Arylation of 2-Mercaptobenzimidazole with Aryl Iodides
Tan, Bryan Yong-Hao,Teo, Yong-Chua
supporting information, p. 2056 - 2060 (2018/09/18)
A practical and efficient strategy for the chemoselective C-S cross-coupling of 2-mercaptobenzimidazole derivatives with a range of substituted aryl iodides is described. Under the optimized conditions of 5 mol% CuI and 100 °C, a variety of S-arylated products were obtained in good to excellent yields (up to 92 %) without the need for assisting ligands.
CHEMICAL COMPOUNDS AS INHIBITORS OF AMYLOID BETA PROTEIN PRODUCTION
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, (2008/06/13)
A compound of the formula I in which Z is O or S; R11 is a halogen atom; R12 is a halogen atom or a trifluoromethyl group; and X is S, SO, SO2, O or NH; R4 is naphthyl, quinolinyl, benzimidazolyl, pyridyl, pyradazinyl, benzoxazolyl or benzothiazolyl, unsubstituted or substituted by one or two substituents selected from a halogen atom, (1-4C)alkyl, (1-4C)alkoxy, nitro, (1-4C)alkoxycarbonyl, halo(1-4C)alkyl, and phenyl; or a pharmaceutically acceptable salt thereof. The compounds are useful as inhibitors of amyloid beta-protein production.
Synthesis of 2-Arylthio- and 2-Arylsulphono-benzimidazoles and of 2,4-Dinitro-12(H)-oxo-benzimidazobenzothiazine as Anthelmintic and Antimicrobial Agents
Rao, K. V. B.,Charles, E. S.,Sharma, Satyavan
, p. 575 - 578 (2007/10/02)
The synthesis and biological activity of a series of 2-arylthiobenzimidazoles (6, 7, 9, 19, 20 and 24), 2-arylsulphonobenzimidazoles (10-18 and 21-23) and 2,4-dinitro-12(H)-oxobenzimidazobenzothiazine (26) are described.None of the compounds shows significant anthelmintic activity while some of the compounds exhibit growth inhibitory activity against different strains of bacteria and fungi.
