395649-41-9

Upstream product

• 10065-72-2 L-Alanine methyl ester 
• 100-52-7 benzaldehyde 
• 2491-20-5 L-alanine methyl ester hydrochloride 

Downstream Products

• 112790-57-5 (S)-2-[(3S,4R)-2-Oxo-3-((S)-2-oxo-4-phenyl-oxazolidin-3-yl)-4-phenyl-azetidin-1-yl]-propionic acid methyl ester 
• 132490-23-4 1'R,2'S,5'R-menthyl r-2R-methoxycarbonyl-2-methyl-c-5R-phenylpyrrolidine-c-4S-carboxylate 
• 31022-10-3 N-benzyl-L-alanine methyl ester 
• 67628-09-5 trimethyl (2S*,5S*)-2-methyl-5-phenyl-2,5-dihydro-1H-pyrrole-2,3,4-tricarboxylate 
• 313344-25-1 2-[4-(benzyloxy)phenylmethyl]furan 
• 1087163-48-1 (2S,3S) methyl 2-(benzylamino)-2-methyl-3-phenyl-3-[(8-quinolyl)sulfonylamino]propanoate 
• 1087163-52-7 (2S,3R) methyl 2-(benzylamino)-2-methyl-3-[(8-quinolyl)sulfonylamino]-3-(thiophen-2-yl)propanoate 

Relevant academic research and scientific papers

Catalytic asymmetric [3+2] cycloaddition of azomethine ylides. Development of a versatile stepwise, three-component reaction for diversity-oriented synthesis

We report a new catalyst system that should enhance the use of enantioselective 1,3-dipolar cycloadditions of azomethine ylides with electronic-deficient olefins in the divergent pathways of diversity-oriented synthesis (DOS). The underlying reaction is o

Sodium borohydride: A versatile reagent in the reductive N-monoalkylation of α-amino acids and α-amino methyl esters

α-Amino acids and α-amino methyl esters are easily converted to their N-monoalkyl derivatives by a reductive condensation reaction using several carbonyl compounds in the presence of sodium borohydride. This reducing agent has shown a wide versatility with minor but essential procedural variations. The reaction allows the α-monodeuterium labeling of the new N-substituent by use of sodium borodeuteride.

Asymmetric Control of 1,3-Dipolar Cycloaddition Reactions with Azomethine Ylides by Means of Proline Esters as Chiral Auxiliary Groups

Upon treatment with triethylamine or DBU in the presence of LiBr, aromatic and aliphatic imines of amino acid esters are converted to N-metalated azomethine ylides.These 1,3-dipoles undergo highly stereoselective cycloadditions with N-acryloyl-(S)-proline