39572-17-3 Usage
Chemical structure
The compound consists of a benzimidazole ring, a thioether group, a phenyl ring, and an ethanone group.
Functional groups
Benzimidazole ring, thioether group, phenyl ring, and ethanone group.
Biological activity
The benzimidazole ring has been found to exhibit biological activity, making the compound potentially useful in drug discovery and development.
Chemical properties
The thioether group provides the compound with unique chemical properties, making it an important intermediate in the synthesis of various organic compounds.
Applications
Commonly used as a building block in the synthesis of various pharmaceuticals and organic compounds due to its unique structure and reactivity.
Versatility
The compound is valuable in both pharmaceutical and chemical industries due to its potential applications and unique properties.
Reactivity
The compound's structure allows for further functionalization and modification in the synthesis of more complex organic compounds.
Potential use
The compound's unique structure and properties make it a promising candidate for the development of new drugs and pharmaceuticals.
Synthesis
The compound can be synthesized through various chemical reactions, utilizing its reactive functional groups for further modification and functionalization.
Check Digit Verification of cas no
The CAS Registry Mumber 39572-17-3 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 3,9,5,7 and 2 respectively; the second part has 2 digits, 1 and 7 respectively.
Calculate Digit Verification of CAS Registry Number 39572-17:
(7*3)+(6*9)+(5*5)+(4*7)+(3*2)+(2*1)+(1*7)=143
143 % 10 = 3
So 39572-17-3 is a valid CAS Registry Number.
InChI:InChI=1/C15H12N2OS/c1-10(18)11-6-8-12(9-7-11)19-15-16-13-4-2-3-5-14(13)17-15/h2-9H,1H3,(H,16,17)
39572-17-3Relevant articles and documents
Ligand-Free CuI-Catalyzed Chemoselective S-Arylation of 2-Mercaptobenzimidazole with Aryl Iodides
Tan, Bryan Yong-Hao,Teo, Yong-Chua
supporting information, p. 2056 - 2060 (2018/09/18)
A practical and efficient strategy for the chemoselective C-S cross-coupling of 2-mercaptobenzimidazole derivatives with a range of substituted aryl iodides is described. Under the optimized conditions of 5 mol% CuI and 100 °C, a variety of S-arylated products were obtained in good to excellent yields (up to 92 %) without the need for assisting ligands.
Visible-light-promoted C-S cross-coupling via intermolecular charge transfer
Liu, Bin,Lim, Chern-Hooi,Miyake, Garret M.
supporting information, p. 13616 - 13619 (2017/11/06)
Disclosed is a mild, scalable, visible-lightpromoted cross-coupling reaction between thiols and aryl halides for the construction of C-S bonds in the absence of both transition metal and photoredox catalysts. The scope of aryl halides and thiol partners includes over 60 examples and therefore provides an entry point into various aryl thioether building blocks of pharmaceutical interest. Furthermore, to demonstrate its utility, this C-S coupling protocol was applied in drug synthesis and latestage modifications of active pharmaceutical ingredients. UV-vis spectroscopy and time-dependent density functional theory calculations suggest that visible-lightpromoted intermolecular charge transfer within the thiolate-aryl halide electron donor-acceptor complex permits the reactivity in the absence of catalyst.
