39575-27-4

Upstream product

• 65-85-0 benzoic acid 
• 613-94-5 benzoic acid hydrazide 
• 135-02-4 ortho-anisaldehyde 

Downstream Products

• 1111148-96-9 dimethyl 3-(triphenyl-λ(5)-phosphanylidene)-2-(N-benzoyl-N'-(2-methoxybenzylidene)hydrazino)succinate 
• 1010796-49-2 N'-(1-(2-methoxyphenyl)but-3-enyl)benzohydrazide 
• 1348312-19-5 2-(2-methoxybenzyl)-5-phenyl-4H-[1,2,4]triazole-3-ylamine 
• 245735-58-4 C₁₁H₁₅NO 
• 1392047-85-6 (2S)-2-(2-methoxyphenyl)-1,2,3,6-tetrahydropyridine 
• 1392047-92-5 C₁₄H₁₇NO₂ 
• 1392048-00-8 (S)-5,6-dihydro-6-(2-methoxyphenyl)pyridin-2(1H)-one 
• 1399210-35-5 (R)-methyl 2-((2-methoxybenzyl)amino)-2-phenylacetate 
• 1399210-33-3 C₂₄H₂₄N₂O₄ 
• 1399210-31-1 C₂₂H₂₀N₂O₂ 
• 1399210-29-7 C₃₀H₂₇N₃O₄ 
• 1399210-27-5 C₃₀H₂₇N₃O₄ 
• 1399210-23-1 C₃₃H₂₇N₃O₃ 

Relevant academic research and scientific papers

Synthesis and characterization of some arylhydrazone ligand and its metal complexes and their potential application as flame retardant and antimicrobial additives in polyurethane for surface coating

Hydrazones are versatile organic ligands and can be synthesized by condensation of hydrazides with carbonyl compounds (aldehydes/ketones). These compounds coordinate to the metal ions via azomethine nitrogen. Hydrazone Schiff's base ligands and their tran

2,5-Diaryloxadiazoles and their precursors as novel inhibitors of cathepsins B, H and L

High levels of cathepsins indicated in various pathological conditions like arthritis, cancer progressions, and atherosclerosis explains the need to explore potential inhibitors of these proteases which can be of great therapeutic significance. We, in the present work, report the synthesis of some 2,5-diaryloxadiazoles from N-subsitutedbenzylidenebenzohydrazides. The synthesized compounds were screened for their inhibitory potential on cathepsins B, H and L. Structure Activity Relationship studies show that 2,5-diaryloxadiazoles were less inhibitory than their precursors. 1i and 2k have been found to be most inhibitory to cathepsins B and L. Their Ki values have been calculated as 11.38 × 10-8 M and 66.4 × 10-8 M for cathepsin B and 4.2 × 10-9 M and 47.31 × 10-9 M for cathepsin L, respectively. However, cathepsin H activity was maximally inhibited by compounds, 1e and 2c with Ki values of 4.4 × 10-7 M and 5.6 × 10-7 M, respectively. Enzyme kinetic studies suggest that these compounds are competitive inhibitors to the enzymes. The results have been compared with docking results obtained using iGemDock.

A catalytic asymmetric Ugi-type reaction with acyclic azomethine imines

An unconventional Ugi: A catalytic asymmetric Ugi-type reaction can be realized by use of N'-alkylbenzohydrazide, instead of a conventional amine, in the presence of an axially chiral dicarboxylic acid. The reaction proceeds through a key acyclic azomethi

5-Ring Heteroaromatic compounds and their use as binding partners for 5-ht5 receptors

The invention relates to 5-ring heteroaromatic compounds of general formula (I), their use for the treatment and/or prevention of diseases, and medicaments containing same.

Synthesizing new hydrazone derivatives and studying their effects on the inhibition of copper corrosion in sodium chloride solutions

O-methoxybenzaldehydebenzoylhydrazone (O-MBH) and bis-(o- methoxybenzaldehyde)-thiocarbodihydrazone (O-MTH) were synthesized. The O-MBH and O-MTH effects on the inhibition of copper corrosion in 3.5% NaCl solution were investigated. Electrochemical measurements showed that the addition of O-MBH and O-MTH decreased the corrosion parameters of copper in the test solutions. The weight loss experiments indicated that O-MBH and O-MTH decreased the corrosion rate of copper. The data pointed out that O-MBH and O-MTH inhibit the copper corrosion in NaCl solution with inhibition efficiency in the order of O-MTH > O-MBH. Copyright Taylor & Francis Group, LLC.

Indium-mediated catalytic enantioselective allylation of N -benzoylhydrazones using a protonated chiral amine

A catalytic enantioselective indium-mediated allylation of N-benzoylhydrazones in conjunction with a protonated chiral amine affording enantioenriched homoallylic amines with an extremely high level of enantioselectivity and chemical yield was developed.

Oxidative cyclization of N-acylhydrazones. Development of highly selective turn-on fluorescent chemodosimeters for Cu2+

A series of N-acylhydrazones were synthesised and found to be "turn-on" fluorescent chemodosimeters for Cu2+. Among the tested transition metal ions such as Cu2+, Pb2+, Zn 2+, Cd2+, Hg2+, and Ni2+, a prominent fluorescence enhancement of up to 1000-fold was only observed for Cu2+ in acetonitrile (CH3CN). This was indicated by an onset of unprecedented structured emission. Detailed experiments established that the highly Cu2+ selective fluorescence enhancement resulted from an oxidative cyclization by Cu2+of the originally nonfluorescent N-acylhydrazones into highly fluorescent rigid 1,3,4-oxadiazoles, n-dope type blocks in optoelectronic materials. The chemodosimeters can be applied to sense Cu2+ at nM levels in CH3CN and sub-M levels in neutral aqueous environments, despite a slower response in the latter case. It is expected that these redox-based chemodosimeters might be of general applicability.