3274-12-2Relevant academic research and scientific papers
A 4-methyl-4-trichloromethyl -2,5-cyclohexadiene-1-one preparation method (by machine translation)
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Paragraph 0068; 0069; 0070; 0071; 0072; 0073; 0074-0076, (2016/10/31)
The invention discloses a method for preparing 4-methyl-4-trichloromethyl-2, 5-cyclohexadiene-1-ketone. The method comprises the following steps that p-cresol and carbon tetrachloride serve as a raw material, aluminum chloride serves as a catalyst, and hydrochloric ether serves as a solvent to have a reaction at the temperature of 33 DEG C to 45 DEG C; water is added into mixed liquor prepared in the S1 to carry out quenching reaction, and the quenching reaction time ranges from 15 min to 45 min; liquor separating is carried out, the liquor separating temperature ranges from 5 DEG C to 20 DEG C, the solvent is removed, and residue is obtained; alcoholic solutions and activated carbon are added into the obtained residue and stirred, the temperature ranges from 50 DEG C to 78 DEG C, the stirring time ranges from 0.5h to 1h, heat filtering is carried out, cooling is carried out until a solid body is not separated out, filtering and drying are carried out, and the 4-methyl-4-trichloromethyl-2, 5-cyclohexadiene-1-ketone is obtained. The preparation method is safe in technological operation, a purification technology is simple, the production period is short, industrialization production is facilitated, raw material cost is low, and the yield is stable.
Dialkyl-substituted dithianes and pesticidal compositions
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, (2008/06/13)
The present invention provides compounds of the formula (I): STR1 wherein m and n are independently selected from 0, 1 or 2, STR2 R is selected from hydrogen, methyl or ethyl; R1 is selected from C1-4 hydrocarbyl substituted by one to five halo atoms, and a group --C C--R9 wherein R9 is a group S(O)w --R10 wherein R10 is trifluoromethyl, methyl or ethyl and w is 0, 1 or 2 or R9 is a C3-5 aliphatic group or an aliphatic group containing up to 5 carbon atoms atoms substituted by C1-4 alkoxy, C2-6 alkoxyalkoxy, C1-8 acyloxy, halo or hydroxy, a group COR11 wherein R11 is hydrogen, C1-4 alkyl, C1-4 alkoxy or a group NR12 R13 wherein R12 and R13 are independently selected from hydrogen, methyl or ethyl, or R9 is SiR14 R15 R16 wherein R14 to R16 are the same or different and each is a C1-4 aliphatic group or R14 and R15 are C1-4 aliphatic groups and R16 is a phenyl group; R2, R3, R7 and R8 are independently selected from hydrogen, methyl or halo; R4a and R4b, R6a and R6b are independently selected from hydrogen, C1-3 alkyl, C2-3 alkenyl or alkynyl each being optionally substituted by halo, cyano or C1-4 alkoxy; cyano, halo or a group COR 11a wherein R11a is hydrogen, C1-4 alkoxy, C1-4 alkyl or a group NR12a R13a wherein R12a and R13a are independently selected from hydrogen, methyl or ethyl; R5a is a non-aromatic hydrocarbyl group containing up to seven carbon atoms, or phenyl each optionally substituted by cyano, halo, C1-4 alkyl, C1-4 haloalkyl, C3-4 cycloalkyl, C1-4 alkoxy or a group S(O)q R17 wherein q is 0, 1 or 2 and R17 is methyl or ethyl and R5b is hydrogen, hydroxy or C1-4 alkyl optionally substituted by alkoxy; and represents --CH--CH-- or --C=C-- which are useful pesticides, processes for their preparation, pesticidal formulations containing them and their use in the control or prevention of pest infestation.
Crystal Structure and Nuclear Quadrupole Resonance. The Bond Length C-Cl and 35Cl NQR
Brummer, Stefanie,Weiss, Alarich
, p. 497 - 513 (2007/10/02)
The intramolecular distances dC-Cl for chlorine bound to sp2 carbon and to sp3 carbon, respectively, and the 35Cl NQR frequencies assigned to the corresponding Cl atoms correlate quite well according to the theory: ν(35Cl) ca. (dC-Cl)-3.The relation is ν(35Cl) = (4 +/- 6) MHz + (166 +/- 31)*1E6*(dC-Cl)-3* MHz*pm3 for 2-C>-Cl and ν(35Cl) = (21 +/- 5) MHz + (101 +/- 25) *1E6 * (dC-Cl)-3 *MHz * pm3 for 3-C>-Cl.The crystal structures and chemical bonds of (1) (4-methyl-4-trichloromethyl-2,5-cyclohexadiene-1-one), (2) (2-chloro-4,5-dimethyl-4-trichloromethyl-2,5-cyclohexadiene-1-one), (3) (4,5-dichloro-1- phenyl-pyridazine-6-one), and (4) ( 2,2,4,5-tetrachloro-cyclopentene-1,3-dione) were studied by single crystal X-ray diffraction and 35Cl nuclear quadrupole resonance (NQR). (1) crystallizes with the space group D152h-Pbca, Z = 8.The lattice constants are a= 1206.0(3) pm, b= 1341.3(3) pm, and c = 1178.8(3) pm. (2) crystallizes monoclinic, space group C52h-P21/c, Z = 4, a = 696.3(3) pm, b = 1404.0(5) pm, c = 1151.4(5) pm, and β = 100.23(1) deg. (3) crystallizes in the orthorhombic space group D42-P212121 , Z = 4, a = 4303(1) pm, b = 586.8(2) pm, and c = 390.5(1) pm. (4) crystallizes cubic, space group T4h-Fd3, with 48 molecules in the unit cell, a = 2181.5(5) pm.The 35Cl NQR spectra were observed for the two 2,5-cyclohexadiene-1-ones, (1) and (2) in the temperature range 77 less equal T/K less melting point.For (3), the 35Cl NQR spectra was determined at T = 77 K and T = 295 K.No phase transition has been found for the three compounds in the temperature range in which the 35Cl NQR spectroscopy was performed.
