39640-62-5

Usage

Uses

Used in Pharmaceutical Industry:
PYRIDINE-4-ACETAMIDE is used as a key building block for the synthesis of various pharmaceuticals, contributing to the development of new drugs and therapeutic agents. Its structural properties make it a versatile component in medicinal chemistry.
Used in Agrochemical Industry:
In the agrochemical sector, PYRIDINE-4-ACETAMIDE serves as a fundamental component in the creation of pesticides, herbicides, and other agricultural chemicals, enhancing crop protection and yield.
Used in Organic Synthesis:
PYRIDINE-4-ACETAMIDE is utilized as an intermediate in organic synthesis for the production of a wide range of organic compounds, showcasing its synthetic utility across different chemical domains.
Used as an Anti-Inflammatory Agent:
PYRIDINE-4-ACETAMIDE is studied for its potential as an anti-inflammatory agent, which, if proven effective, could be used in the treatment of various inflammatory conditions.
Used as an Analgesic Agent:
PYRIDINE-4-ACETAMIDE is also being investigated for its analgesic properties, suggesting a possible application in pain management and relief therapies.

InChI:InChI=1/C7H8N2O/c8-7(10)5-6-1-3-9-4-2-6/h1-4H,5H2,(H2,8,10)

Upstream product

• 54401-85-3 pyridin-4-yl-acetic acid ethyl ester 
• 123-91-1 1,4-dioxane 
• 100-43-6 4-vinylpyridine 
• 7664-41-7 ammonia 
• 7732-18-5 water 
• 13121-99-8 pyridin-4-ylacetonitrile 
• 28356-58-3 pyridine-4-acetic acid 
• 29800-89-3 methyl 4-pyridineacetate 

Downstream Products

• 54401-85-3 pyridin-4-yl-acetic acid ethyl ester 
• 13258-63-4 4-(2-Aminoethyl)pyridine 

Relevant academic research and scientific papers

Aryl-indolyl maleimides as inhibitors of CaMKIIδ. Part 1: SAR of the aryl region

A family of aryl-substituted maleimides was prepared and studied for their activity against calmodulin dependant kinase. Inhibitory activities against the enzyme ranged from 34 nM to >20 μM and were dependant upon both the nature of the aryl group and the hydrogen bond donating potential of the maleimide ring. Key interactions with the kinase ATP site and hinge region were found to be consistent with homology modeling predictions.

Structural Factors Affecting the Basicity of ω-Pyridylalkanols, ω-Pyridylalkanamides and ω-Pyridylalkylamines

The present paper describes the preparation by conventional methods (when not available commercially) and the pKa-determination of the α-, β- and γ-isomers of pyridylethanamide, 3-pyridylpropanamide, 4-pyridylbutanamide, 5-pyridylpentanamide, pyridylmethanol, 2-pyridylethanol, 3-pyridylpropanol, 4-pyridylbutanol, 5-pyridylpentanol, pyridylmethylamine, 2-pyridylethylamine, 3-pyridylpropylamine, 4-pyridylbutylamine, and 5-pyridylpentylamine.While a field effect accounts for many variations in pKa as a function of chain length, marked inductive effects are operative in some methyl and ethyl homologs.The pKa-decreasing influence of an intramolecular H-bond is also apparent in some lower homologs belonging to the α-series.

11a-Methano-TXA compounds

The present invention provides novel 11a-methano-TXA compounds and intermediates and processs for their preparation. Further provided are methods for using these novel TXA analogs as inhibitors of thromboxane synthetase, rendering these analogs useful for a variety of pharmacological purposes. These pharmacological uses include anti-inflammatory, anti-thromobitc, and anti-asthma indications.