39643-69-1

Upstream product

• 93-89-0 benzoic acid ethyl ester 
• 2460-58-4 2-hydroxy-4-nitrobenzaldehyde 
• 613-94-5 benzoic acid hydrazide 
• 93-58-3 benzoic acid methyl ester 
• 65-85-0 benzoic acid 
• 97-51-8 5-Nitrosalicylaldehyde 

Downstream Products

• 1049009-50-8 2-benzoyl-5-nitrobenzaldehyde 
• 108616-70-2 Fe(HO(NO₂)C₆H₃CHNNHC(O)C₆H₅)SO₄(H₂O)=Fe(HO(NO₂)C₆H₃CHNNHC(O)C₆H₅)SO₄*H₂O 
• 91838-41-4 Zr(OH)2(OC₆H₃(NO₂)CHNNHC(O)C₆H₅)2 

Relevant academic research and scientific papers

New magnetic supported hydrazone Schiff base dioxomolybdenum (VI) complex: An efficient nanocatalyst for epoxidation of cyclooctene and norbornene

A new dioxomolybdenum (VI) complex with tridentate hydrazone Schiff base ligand (H2L) derived from 2-hydroxy-5-nitrobenzaldehyde and benzhydrazide was synthesized and designated as [MoO2L (DMF)]·2H2O. The Fe3O4@SiO2-CPS-L-MoO2 (EtOH) nanocatalyst was successfully prepared by grafting H2L ligand on modified Fe3O4 nanoparticles followed by reacting with MoO2 (acac)2. The complex and nanocatalyst were characterized by various techniques such as elemental analysis, mass, FT-IR, UV–Vis, 1H NMR, 13C{1H}-NMR, TGA, XRD, XPS, TEM, SEM and VSM. The catalytic activity of [MoO2L (DMF)]2H2O and Fe3O4@SiO2-CPS-L-MoO2 (EtOH) were evaluated for the oxidation of various alkenes (cyclooctene, norbornene, cyclohexene, styrene and α-methyl styrene) in the presence of tert-butylhydroperoxide as oxidant. The results revealed that the catalysts were especially efficient for oxidation of cyclooctene and norbornene with 100% selectivity towards corresponding epoxide product. Fe3O4@SiO2-CPS-L-MoO2 (EtOH) showed higher catalytic activity, shorter reaction time and higher turnover number (TON) compared with homogeneous complex [MoO2L (DMF)]·2H2O. Moreover, simple magnetic recovery from the reaction mixture and reuse for several times with no significant loss in activity were other advantages of the nanocatalyst.

Characterization and antidiabetic activity of salicylhydrazone Schiff base vanadium(IV) and (V) complexes

Twenty-four oxidovanadium(IV,V) complexes with tridentate Schiff base ligands based on 5-nitrosalicylaldehyde, 5-methoxysalicylaldehyde, or 5-sulfosalicylaldehyde and respective hydrazide were isolated, and characterized using physicochemical and spectros

Multiple Hydrogen Bonds Promoted ESIPT and AIE-active Chiral Salicylaldehyde Hydrazide

The simpler, the better! A series of simple and highly fluorescent salicylaldehyde hydrazide molecules (41 samples) have been designed and prepared. Even though these soft materials contain a very small π-conjugated system, they can go through multiple intramolecular and intermolecular hydrogen bonds promoted excited-state intramolecular proton-transfer (ESIPT) to display strong blue, green, yellow, and orange aggregation-induced emission (AIE) with large Stokes shifts (up to 184 nm) and high fluorescence quantum yields (Ф up to 0.20). Unusual mechanochromic fluorescence enhancements are also found in some solid samples. Through coordination, hydrogen and halogen bonds, these flexible molecules can be used as Mg2+ (Ф up to 0.46) probes, universal anion (Ф up to 0.14) and unprotected amino acids (Ф up to 0.16) probes, and chiral diamine (enantiomeric selectivity and Ф up to 0.36 and 0.062, respectively) receptors. Combining their advantages of AIE and biocompatibility, these low cytotoxic dyes have potential application in living cell imaging. Furthermore, the effects of different functional groups on the molecule arrangement, ESIPT, AIE, probe, and chiral recognition properties are also examined, which provide a simple and bright paradigm for the design of multiple-stimuli-responsive smart materials.

Synthesis and antifungal activity of substituted salicylaldehyde hydrazones, hydrazides and sulfohydrazides

Efficient synthetic procedures for the preparation of acid hydrazines and hydrazides were developed by converting the corresponding carboxylic acid into the methyl ester catalyzed by Amberlyst-15, followed by a reaction with hydrazine monohydrate. Sulfohydrazides were prepared from the corresponding sulfonyl chlorides and hydrazine monohydrate. Both of these group of compounds were condensed with substituted salicylaldehydes using gradient concentration methods that generated a large library of hydrazone, hydrazide and sulfohydrazide analogs. Antifungal activity of the prepared analogs showed that salicylaldehyde hydrazones and hydrazides are potent inhibitors of fungal growth with little to no mammalian cell toxicity, making these analogs promising new targets for future therapeutic development.

SYNERGISTIC FUNGICIDAL COMPOSITIONS INCLUDING HYDRAZONE DERIVATIVES AND COPPER

The present invention relates to the use of mixtures containing hydrazone compounds and copper for controlling the growth of fungi.

A versatile and regiospecific synthesis of functionalized 1,3-diarylisobenzofurans

(Chemical Equation Presented) A convenient, versatile, and regiospecific synthesis of functionalized 1,3-diarylisobenzofurans has been developed. It involves chemoselective addition of arylmagnesium reagents to the aldehyde function of o-aroylbenzaldehydes, themselves readily obtained by lead tetraacetate oxidation of N-aroylhydrazones of salicylaldehydes. Various functional groups, including nitro, iodo, or ester functionalities, have thus been positioned with complete regiospecificity on the 1,3-diphenylisobenzofuran backbone.