3967-18-8

Usage

Uses

Used in Chemical Synthesis:
Z-L-glutamic acid γ-tert·butyl α-benzyl ester is used as a synthetic intermediate for its ability to participate in various chemical reactions, contributing to the formation of complex molecules and compounds.
Used in Pharmaceutical Industry:
Z-L-glutamic acid γ-tert·butyl α-benzyl ester is used as a building block for the development of new pharmaceuticals, leveraging its unique structure to create novel drug candidates with potential therapeutic applications.
Used in Research and Development:
Z-L-glutamic acid γ-tert·butyl α-benzyl ester is used as a research tool in academic and industrial laboratories, facilitating the exploration of new chemical pathways and the discovery of innovative materials and compounds.

Upstream product

• 3886-08-6 5-tert-butyl N-benzyloxycarbonyl-L-glutamate 
• 100-51-6 benzyl alcohol 
• 98946-18-0 tert-Butyl 2,2,2-trichloroacetimidate 
• 3705-42-8 Cbz-(L)-Glu-OBn 
• 115-11-7 isobutene 

Downstream Products

• 3886-08-6 5-tert-butyl N-benzyloxycarbonyl-L-glutamate 
• 167319-89-3 benzyl L-<(2-benzyloxycarbonyl)amino>-5-hydroxypentanoate 
• 3705-42-8 Cbz-(L)-Glu-OBn 
• 1373233-97-6 benzyl (S)-5-[N-acetyl-N-(tert-butoxy)amino]-2-[N-(benzyloxycarbonyl)amino]pentanoate 
• 1373233-96-5 benzyl (S)-2-[N-(benzyloxycarbonyl)amino]-5-[N-(tert-butoxy)amino]pentanoate 
• 1373233-95-4 benzyl (S)-2-[N-(benzyloxycarbonyl)amino]-5-[N-(tert-butoxy)-N-(2-nitrophenylsulfonyl)amino]pentanoate 
• 13155-43-6 N--L-glutaminsaeure-γ-tert.-butylester 
• 2419-56-9 L-glutamic acid 5-tert-butyl ester 

Relevant academic research and scientific papers

Synthesis and application of an Nδ-acetyl-N δ-hydroxyornithine analog: Identification of novel metal complexes of deferriferrichrysin

Synthesis of Fmoc-protected Nδ-acetyl-N δ-(tert-butoxy)-l-ornithine has revealed it to be a metal-chelating amino-acid precursor. This protected amino acid was compatible with the preparation of ferrichrome peptides by standard Fmoc-

Enzymatic removal of carboxyl protecting groups. 2. Cleavage of the benzyl and methyl moieties

Enzymes are versatile reagents for the efficient removal of methyl and benzyl protecting groups. An esterase from Bacillus subtilis (BS2) and a lipase from Candida antarctica (CAL-A) allow a mild and selective removal of these moieties in high yields without affecting other functional groups.

2-Phenyl isopropyl and t-butyl trichloroacetimidates: Useful reagents for ester preparation of N-protected amino acids under neutral conditions

2-Phenylisopropyl and t-butyl trichloroacetamidates 1 and 2 are useful reagents for the esterification of N-protected aminoacids under mild neutral conditions. In the case of hydroxyl-containing amino acids dialkylation occurs but no selectivity could be obtained.