39672-01-0

Upstream product

• 57-14-7 N,N-Dimethylhydrazine 
• 502-42-1 cycloheptanone 

Downstream Products

• 502-42-1 cycloheptanone 
• 1323770-21-3 C₂₀H₂₂O₂ 
• 1313885-47-0 2-butylcycloheptanone (S)-Mosher's ester 
• 101276-70-4 2-(3-phenyl-propyl)-cycloheptanone 

Relevant academic research and scientific papers

A Complementary Process to Pauson-Khand-Type Annulation Reactions for the Construction of Fully Substituted Cyclopentenones

A complementary process to the Pauson-Khand annulation is described that is well suited to forging densely substituted/oxygenated cyclopentenone products (including fully substituted variants). The reaction is thought to proceed through a sequence of meta

Tertiary Enamide-Triggered SEAr: Domino Allylation and Enamine-Type Addition

Two unprecedented domino reactions are described, starting from ketospiro-enesulfonamides. By treatment with ZrCl4 and allylsilane, an intramolecular electrophilic aromatic substitution and subsequent allylation is observed. By treatment with TiCl4 and allylsilane, a double enamine-type reaction takes place, thus creating simultaneously four contiguous stereogenic centers diastereoselectively.

The asymmetric alkylation of dimethylhydrazones; Intermolecular chirality transfer using sparteine as chiral ligand

The asymmetric alkylation of ketones represents a fundamental transformation in organic chemistry. Chiral auxiliaries have been used almost exclusively for this transformation. Herein we describe a strategy for the generation of enantiomerically enriched α-alkylated ketones up to an er of 83:17, using a chiral ligand protocol. This journal is

Intramolecular reductive ketone-alkynoate coupling reaction promoted by (η2-propene)titanium

Intramolecular reductive coupling of cycloalkanones tethered to alkynoates in the presence of (η2-propene)titanium was successfully performed to provide hydroxy-esters in a diastereoselective manner. Subsequent lactonization afforded angularly

Gold-catalyzed 1,3-acyloxy migration/5-exo-dig cyclization/1,5-acyl migration of diynyl esters

Working three shifts: Polyconjugated δ-diketones are formed stereoselectively in high yields by the gold-catalyzed rearrangement of 1,6-diyn-3-yl esters. This cascade involves a 1,3-sigmatropic acyloxy shift, a 5-exo-dig cyclization of the resulting allenyne, and an unprecedented 1,5-sigmatropic shift of an acyl fragment. The usefulness of the products was shown by an efficient acid-catalyzed transformation into a complex polycyclic framework. Copyright

The 2-(2-Azidoethyl)cycloalkanone strategy for bridged amides and medium-sized cyclic amine derivatives in the Aubé-Schmidt reaction

2-(2-Azidoethyl)cycloalkanones afford bridged lactams in the Aubé-Schmidt reaction, sometimes in excellent yield, and solvolysis yields derivatives of medium-ring amines. Attempts to divert the Schmidt reaction with an arene-mediated fragmentation of the normal Schmidt intermediate have led to an initial example. Georg Thieme Verlag Stuttgart.

Photoinduced atom-transfer cyclization of α-iodocycloalkanones bearing an allenyl side chain

(Chemical Equation Presented) Irradiation of α-iodocycloalkanones bearing an allenyl side chain with a sunlamp effected atom-transfer cyclization to give cyclized products in good yield. A mechanism, involving radical atom-transfer cyclization accompanied

New cascade reactions starting from acetylenic ω-ketoesters: An easy access to electrophilic allenes and to 1,3-bridgehead ketones

Acetylenic ω-ketoesters bearing a three carbon-carbon bond spacer reacted smoothly with tetra-n-butylammonium fluoride and with potassium tert-butoxide to afford either electrophilic allenes or 1,3-bridgehead ketones, the latter being potentially useful m

Enzymatic resolution of bicyclo[n.1.0]alkan-1-ols derivatives: Preparation of optically active α-substituted α-methylcycloalkanones

Optically active α-methyl α-substituted cycloalkanones are prepared by a chemoenzymatic sequence which involves a Lipozyme-catalyzed transesterification of 1-(chloroacetoxy)bicyclo[n.1.0]alkanes and ring opening of these cyclopropanol derivatives.