3969-61-7

Basic information

• Product Name: (2,2-DIMETHYL-[1,3]DIOXOLAN-4-YL)-(5-HYDROXYMETHYL-2,2-DIMETHYL-[1,3]DIOXOLAN-4-YL)-METHANOL
• Synonyms: 1,2:4,5-DI-O-ISOPROPYLIDENE-D-MANNITOL;1,2:4,5-DI-O-ISOPROPYLIDENE-ALPHA-D-MANNITOL;(2,2-DIMETHYL-[1,3]DIOXOLAN-4-YL)-(5-HYDROXYMETHYL-2,2-DIMETHYL-[1,3]DIOXOLAN-4-YL)-METHANOL;(S)-((R)-2,2-DIMETHYL-[1,3]DIOXOLAN-4-YL)-((4R,5S)-5-HYDROXYMETHYL-2,2-DIMETHYL-[1,3]DIOXOLAN-4-YL)-METHANOL;1,2:4,5-Bis-O-(1-Methylethylidene)-D-Mannitol;NSC 93066
• CAS NO: 3969-61-7
• Molecular Formula: C₁₂H₂₂O₆
• Molecular Weight: 262.3
• Product Categories: 13C & 2H Sugars;Carbohydrates & Derivatives
• Mol File: 3969-61-7.mol
• Article Data: 2

Chemical Properties

• Melting Point: 50-51°C
• Boiling Point: 367.7°Cat760mmHg
• Flash Point: 176.2°C
• Appearance: /
• Density: 1.159g/cm³
• Vapor Pressure: 6.71E-07mmHg at 25°C
• Refractive Index: 1.469
• Storage Temp.: -20?C Freezer
• Solubility: Dichloromethane, Ethyl Acetate
• CAS DataBase Reference: (2,2-DIMETHYL-[1,3]DIOXOLAN-4-YL)-(5-HYDROXYMETHYL-2,2-DIMETHYL-[1,3]DIOXOLAN-4-YL)-METHANOL(CAS DataBase Reference)
• NIST Chemistry Reference: (2,2-DIMETHYL-[1,3]DIOXOLAN-4-YL)-(5-HYDROXYMETHYL-2,2-DIMETHYL-[1,3]DIOXOLAN-4-YL)-METHANOL(3969-61-7)
• EPA Substance Registry System: (2,2-DIMETHYL-[1,3]DIOXOLAN-4-YL)-(5-HYDROXYMETHYL-2,2-DIMETHYL-[1,3]DIOXOLAN-4-YL)-METHANOL(3969-61-7)

Safety Data

• Hazardous Substances Data: 3969-61-7(Hazardous Substances Data)

Usage

Chemical Properties

White Solid

Uses

1,2:4,5-Di-O-isopropylidene-D-mannitol (cas# 3969-61-7) is a compound useful in organic synthesis.

InChI:InChI=1/C12H22O6/c1-11(2)15-6-8(17-11)9(14)10-7(5-13)16-12(3,4)18-10/h7-10,13-14H,5-6H2,1-4H3

Upstream product

• 4306-35-8 1,2-O-isopropylidene-D-glucitol 
• 67-64-1 acetone 
• 69-65-8 mannitol 
• 77-76-9 2,2-dimethoxy-propane 
• 91667-55-9 1,2:3,6:4,5-tri-O-isopropylidene-D-mannitol 
• 55549-04-7 1,4-di-O-acetyl-2,3:5,6-di-O-isopropylidene-D-glucitol 

Downstream Products

• 96075-43-3 O¹,O⁶-dibenzoyl-O²,O³;O⁴,O⁵-diisopropylidene-galactitol 
• 7115-20-0 DL-O¹,O⁴-dibenzoyl-O²,O³;O⁵,O⁶-diisopropylidene-galactitol 
• 71696-37-2 DL-O¹,O²;O⁴,O⁵-diisopropylidene-O³,O⁶-bis-(toluene-4-sulfonyl)-galactitol 
• 140156-32-7 1-O-benzyl-2,3:5,6-di-O-isopropylidene-D-mannitol 
• 89755-44-2 Toluene-4-sulfonic acid (4R,5S)-5-[(R)-((R)-2,2-dimethyl-[1,3]dioxolan-4-yl)-hydroxy-methyl]-2,2-dimethyl-[1,3]dioxolan-4-ylmethyl ester 
• 158513-85-0 4-O-benzyl-2,3:4,6-di-O-isopropylidene-D-gulitol 
• 71696-42-9 DL-O²,O³;O⁵,O⁶-diisopropylidene-1-iodo-O⁴-(toluene-4-sulfonyl)-1-deoxy-galactitol 
• 1189331-54-1 N-tert-butoxycarbonyl-1,4-dideoxy-2,3-O-isopropylidene-5-O-benzyl-1,4-imino-D-ribitol 
• 1189331-56-3 N-tert-butoxycarbonyl-1,4-dideoxy-2,3-O-isopropylidene-5-O-(p-phenylbenzyl)-1,4-imino-D-ribitol 
• 1189331-55-2 1,4-dideoxy-5-O-benzyl-1,4-imino-D-ribitol 
• 114827-01-9 benzyl [fluoro 3-deoxy-4,5-7,8-di-O-isopropylidene-α-D-manno-octulopyranosid]onate 
• 1392224-73-5 benzyl [N-benzyloxycarbonyl-3-amino-propyl 3-deoxy-4,5-7,8-di-O-isopropylidene-α-D-mannooctulopyranosid]onate 
• 1392224-71-3 benzyl [N-benzyloxycarbonyl-3-amino-propyl 4-O-benzyl-3-deoxy-7,8-O-isopropylidene-α-D-manno-octulopyranosid] onate 
• 1392224-74-6 C₂₉H₃₇NO₁₀ 

Relevant articles and documents

THE SYNTHESIS OF 1,2:5,6-DI-O-ISOPROPYLIDENE-D-MANNITOL: A COMPARATIVE STUDY

Three different methods of acetonation of D-mannitol using (a) acetone and zinc chloride, (b) 2,2-dimethoxypropane, 1,2-dimethoxyethane, and tin(II)chloride, and (c) 2-methoxypropane, N,N-dimethylformamide, and p-toluenesulfonic acid were studied in detail and compared, using gas-liquid chromatographic techniques.In each reaction, isomeric diacetals are formed, but method a gives the 1,2:5,6-diacetal in the highest yield (63percent).Methods b and c give a more complex mixture of acetals than proposed in the literature, and both methods are less economical than a.A new 1,2:3,6:4,5-tri-O-isopropylidene-D-mannitol could be separated, and its graded hydrolysis was compared to that of the 1,2:3,4:5,6-triacetal.