39719-33-0

Basic information

• Product Name: 2-methyl-N-phenylbenzohydrazonoyl chloride
• Synonyms: 2-methyl-N-phenylbenzohydrazonoyl chloride
• CAS NO: 39719-33-0
• Molecular Weight: 244.724
• Mol File: 39719-33-0.mol
• Article Data: 6

Chemical Properties

• CAS DataBase Reference: 2-methyl-N-phenylbenzohydrazonoyl chloride(CAS DataBase Reference)
• NIST Chemistry Reference: 2-methyl-N-phenylbenzohydrazonoyl chloride(39719-33-0)
• EPA Substance Registry System: 2-methyl-N-phenylbenzohydrazonoyl chloride(39719-33-0)

Safety Data

• Hazardous Substances Data: 39719-33-0(Hazardous Substances Data)

Upstream product

• 58537-47-6 2-methyl-N′-phenylbenzohydrazide 
• 118-90-1 ortho-methylbenzoic acid 
• 100-63-0 phenylhydrazine 
• 529-20-4 2-methylphenyl aldehyde 
• 89-95-2 2-methyl-benzyl alcohol 
• 59473-50-6 o-MeC₆H₄CHNNHC₆H₅ 
• 933-88-0 ortho-toluoyl chloride 

Relevant articles and documents

Synthesis of 3 H-1,2,4-Triazol-3-ones via NiCl2-Promoted Cascade Annulation of Hydrazonoyl Chlorides and Sodium Cyanate

A nickel-promoted cascade annulation reaction for the facile synthesis of 3H-1,2,4-triazol-3-ones from readily available hydrazonoyl chlorides and sodium cyanate has been developed. The transformation occurs through a cascade nickel-promoted intermolecular nucleophilic addition-elimination process, intramolecular nucleophilic addition, and a hydrogen-transfer sequence. The method has been successfully applied for the construction of the core skeleton of the angiotensin II antagonist.

Facile One-Pot Transformation of Primary Alcohols into 3-Aryl- and 3-Alkyl-isoxazoles and -pyrazoles

Various primary alcohols were smoothly transformed into 3-aryl- and 3-alkylisoxazoles in good yields in one pot by successive treatment with PhI(OAc) 2 in the presence of TEMPO, NH 2 OH, and then NCS, followed by reaction with alkynes in the presence of Et 3 N. Similarly, various primary alcohols were smoothly transformed into 3-aryl- and 3-alkylpyrazoles in good yields in one pot by successive treatment with PhI(OAc) 2 in the presence of TEMPO, PhNHNH 2, and then NCS and decyl methyl sulfide, followed by reaction with alkynes in the presence of Et 3 N. Thus, both 3-aryl- and 3-alkylisoxazoles, and 3-aryl- and 3-alkylpyrazoles could be prepared from readily available primary alcohols in one pot under transition-metal-free conditions.

Method of use, composition, and compounds

Certain benzoyl chloride phenylhydrazones have been found to be active against insects and mites. The benzoyl ring and the phenylhydrazone ring can be substituted with a halogen atom, a nitro group, or an alkyl group of from 1 to 6 carbon atoms, inclusive