397322-46-2

Basic information

• Product Name: 5-BroMo-3-Methylquinoline
• Synonyms: 5-BroMo-3-Methylquinoline
• CAS NO: 397322-46-2
• Molecular Formula: C₁₀H₈BrN
• Molecular Weight: 222.08122
• Mol File: 397322-46-2.mol
• Article Data: 3

Chemical Properties

• Boiling Point: 313.8±22.0 °C(Predicted)
• Appearance: /
• Density: 1.488±0.06 g/cm3(Predicted)
• Storage Temp.: Sealed in dry,Room Temperature
• PKA: 4.07±0.23(Predicted)
• CAS DataBase Reference: 5-BroMo-3-Methylquinoline(CAS DataBase Reference)
• NIST Chemistry Reference: 5-BroMo-3-Methylquinoline(397322-46-2)
• EPA Substance Registry System: 5-BroMo-3-Methylquinoline(397322-46-2)

Safety Data

• Hazardous Substances Data: 397322-46-2(Hazardous Substances Data)

Usage

General Description

5-Bromo-3-methylquinoline is a chemical compound with the molecular formula C10H8BrN. It is a derivative of quinoline, which is a heterocyclic aromatic compound. The addition of a bromine atom and a methyl group to the quinoline structure gives 5-bromo-3-methylquinoline its unique chemical properties. 5-BroMo-3-Methylquinoline is used in various chemical and pharmaceutical applications, particularly as a building block in the synthesis of other organic compounds. Its chemical structure and reactivity make it a valuable tool in organic chemistry research and drug development. 5-Bromo-3-methylquinoline is also used as a fluorescent probe for studying biological processes and as a precursor in the production of pharmaceutical drugs and agrochemicals.

Upstream product

• 144-55-8 sodium hydrogencarbonate 

Downstream Products

• 20357-21-5 2-bromo-6-nitrobenzaldehyde 

Relevant articles and documents

WDR5 INHIBITORS AND MODULATORS

Isoquinolmone compounds and derivatives inhibit WDR5 and associated protein-protein interactions, and the compounds and their pharmaceutical compositions are useful for treating disorders and conditions in a subject, such as cancer cell proliferation.

Pyrrole derivatives

Pyrrole derivatives represented by the following formula: wherein Ring Z is an optionally substituted pyrrole ring, etc.; W2 is —CO—, —SO2—, an optionally substituted C1-C4 alkylene, etc.; Ar2 is an optionally substituted aryl, etc.; W2 and Ar1 mean the following (1) and (2): (1) W1 is an optionally substituted C1-C4 alkylene, etc.; Ar1 is an optionally substituted bicyclic heteroaryl having 1 to 4 nitrogen atoms as ring-forming atoms: (2) W1 is an optionally substituted C2-C5 alkylene, an optionally substituted C2-C5 alkenylene, etc.; and Ar1 is an aryl or monocyclic heteroaryl, which are substituted by carboxyl, an alkoxycarbonyl, etc. at the ortho- or meta-position thereof with respect to the binding position of W1, or a pharmaceutically acceptable salt thereof These compounds are useful as medicaments such as a fibrosis inhibitor for organs or tissues.