397322-46-2

Usage

Uses

Used in Organic Chemistry Research:
5-Bromo-3-methylquinoline is utilized as a building block for the synthesis of various organic compounds, contributing to the advancement of organic chemistry through its unique reactivity and structural properties.
Used in Pharmaceutical Development:
In the pharmaceutical industry, 5-Bromo-3-methylquinoline serves as a precursor in the production of drugs, leveraging its chemical properties to facilitate the creation of novel medicinal agents.
Used as a Fluorescent Probe in Biological Research:
5-Bromo-3-methylquinoline is employed as a fluorescent probe, enabling the study of biological processes through its ability to emit light when exposed to specific wavelengths. This application aids researchers in visualizing and understanding complex biological phenomena.
Used in the Production of Agrochemicals:
Additionally, 5-Bromo-3-methylquinoline is used as a precursor in the manufacturing of agrochemicals, indicating its broad applicability across different sectors, including agriculture for the development of pesticides and other related products.

Upstream product

• 144-55-8 sodium hydrogencarbonate 

Downstream Products

• 20357-21-5 2-bromo-6-nitrobenzaldehyde 

Relevant academic research and scientific papers

WDR5 INHIBITORS AND MODULATORS

Isoquinolmone compounds and derivatives inhibit WDR5 and associated protein-protein interactions, and the compounds and their pharmaceutical compositions are useful for treating disorders and conditions in a subject, such as cancer cell proliferation.

FIBROSIS INHIBITOR

Medicament being useful as a fibrosis inhibitor for organs or tissues, which comprises a compound of the formula (I): wherein Ring Z is optionally substituted pyrrole ring, etc.; W2 is -CO-, -SO2-, optionally substituted C1-C4 alkylene, etc.; Ar2 is optionally substituted aryl, etc.; W1 and Ar1 mean the following (1) and (2):(1) W1 is optionally substituted C1-C4 alkylene, etc.; Ar1 is optionally substituted bicyclic heteroaryl having 1 to 4 nitrogen atoms as ring-forming atoms:(2) W1 is optionally substituted C2-C5 alkylene, optionally substituted C2-C5 alkenylene, etc.; and Ar1 is aryl or monocyclic heteroaryl, which is substituted by carboxyl, alkoxycarbonyl, etc. at the ortho- or meta-position thereof with respect to the binding position of W1, or a pharmaceutically acceptable salt thereof.

Pyrrole derivatives

Pyrrole derivatives represented by the following formula: wherein Ring Z is an optionally substituted pyrrole ring, etc.; W2 is —CO—, —SO2—, an optionally substituted C1-C4 alkylene, etc.; Ar2 is an optionally substituted aryl, etc.; W2 and Ar1 mean the following (1) and (2): (1) W1 is an optionally substituted C1-C4 alkylene, etc.; Ar1 is an optionally substituted bicyclic heteroaryl having 1 to 4 nitrogen atoms as ring-forming atoms: (2) W1 is an optionally substituted C2-C5 alkylene, an optionally substituted C2-C5 alkenylene, etc.; and Ar1 is an aryl or monocyclic heteroaryl, which are substituted by carboxyl, an alkoxycarbonyl, etc. at the ortho- or meta-position thereof with respect to the binding position of W1, or a pharmaceutically acceptable salt thereof These compounds are useful as medicaments such as a fibrosis inhibitor for organs or tissues.