397333-50-5

Upstream product

• 705-76-0 3,5-dimethoxybenzyl alcohol 
• 6652-32-0 3,5-dimethoxybenzylchloride 
• 121-45-9 phosphorous acid trimethyl ester 
• 877-88-3 3,5-dimethoxybenzyl bromide 

Downstream Products

• 223386-36-5 (E)-1-(3,5-dimethoxyphenyl)-2-(4-pyridyl)ethene 
• 89946-15-6 trans-1-(3,5-dimethoxyphenyl)-2-(3,4,5-trimethoxyphenyl)ethene 
• 83088-26-0 (E)-tetramethylpiceatannol 
• 708228-53-9 (E)-2',3,5,5'-tetramethoxystilbene 
• 20767-18-4 cis-trans-3,3',4',5-tetramethoxystilbene 
• 22255-22-7 3,5,4'-trimethoxystilbene 
• 20578-92-1 (E)-3,5,2',4'-tetramethoxystilbene 
• 22255-22-7 3,5,4'-trimethoxy-trans-stilbene 
• 397333-51-6 (E)-2-(3,5-dimethoxystyryl)-5-methoxyphenol 

Relevant academic research and scientific papers

Preparation method for health product pterostilbene

The invention provides a preparation method for a health product pterostilbene. According to the invention, 1, a deprotection method used in the invention is green, environment-friendly and pollution-free, the preparation method is almost free of production of waste gas, waste water and industrial residues, and the product 1,4-pentadiene has economic value; 2, a catalyst used in the invention has good cycle repeatability and can be cyclically used 50 times or more; 3, the preparation method is simple in operation requirements, mild in reaction conditions, good in specificity, simple in post-treatment and purification of the product, and suitable for industrial production; and 4, the pterostilbene prepared by using the method is free of impurities like 3-methoxy-4',5-dihydroxystilbene and resveratrol and has high purity.

Synthesis method of piceatannol

The present invention provides a synthesis method of piceatannol. The method comprises the following steps: reacting 3,5-dimethoxybenzyl alcohol with phosphorus oxychloride to obtain 3,5-dimethoxybenzyl chloride; adding the obtained 3,5-dimethoxybenzyl ch

Method for preparing resvertrol (by machine translation)

The invention discloses method for preparing resvertrol, in order to 3,5-dimethoxy-methanol as the raw material, through chloropivaloyl, to obtain 3,5-dimethoxy oxygen radical chlorine animal pen, through the 3,5-dimethylbenzaldehyde by oxygen radical chlorine animal pen 3, the 4 [...], 5-trimethoxy stilbene, reuse alchlor and triethylamine so as to obtain crude product resveratrol methyl, then the ethanol and water is recrystallized to get resveratrol works. This invention, through the triphosgene 3,5-dimethoxy-methanol chloropivaloyl, instead of ethanol using sodium hydride and sodium, synthetic 3, the 4 [...], 5-trimethoxy stilbene, reuse alchlor and triethylamine so as to obtain crude product resveratrol methyl, then the ethanol and water is recrystallized to get resveratrol works, preparation method has high yield, low cost. (by machine translation)

Design, synthesis, and discovery of novel trans-stilbene analogues as potent and selective human cytochrome P450 1B1 inhibitors

A series of trans-stilbene derivatives containing a 3,5-dimethoxyphenyl moiety were prepared through a new efficient solution phase synthetic pathway, and their inhibitory activities were evaluated on human cytochrome P450s (CYP) 1A1, 1A2, and 1B1 to find a potent and selective CYP1B1 inhibitor. We found that a substituent at the 2-position of the stilbene skeleton plays a very important role in discriminating between CYP1As and CYP1B1. Among the compounds tested, the most selective and potent CYP1B1 inhibitor was 2,3',4,5'-tetramethoxystilbene. Compound 7j, 2-[2-(3,5-dimethoxy-phenyl)vinyl]thiophene, showed greater inhibitory activities but had a lower selectivity toward all of the CYPls tested.