39741-26-9

Basic information

• Product Name: N-BENZOYL-L-ASPARTIC ACID-Beta-METHYL ESTER
• Synonyms: N-BENZOYL-L-ASPARTIC ACID-Beta-METHYL ESTER;N-Benzooyl-L-aspartic acid-B-methyl ester;N-Benzoyl-L-Aspartic Acid Methyl Ester;N-BENZOYL-ASPARTIC ACID-4-METHYL ESTER;N-BENZOY-L-ASPARTIC ACID-BETA-METHYL ESTER;N-BENZOOYL-L-ASPARTIC ACID--METHYL ESTER;N-Benzooyl-L-asparticacid-beta-methylester;N-Benzoyl-L-aspartic acid 4-methyl ester
• CAS NO: 39741-26-9
• Molecular Formula: C₁₂H₁₃NO₅
• Molecular Weight: 251.23532
• Mol File: 39741-26-9.mol
• Article Data: 4

Chemical Properties

• Boiling Point: 531.914 °C at 760 mmHg
• Flash Point: 275.492 °C
• Appearance: /
• Density: 1.293 g/cm³
• Storage Temp.: 2-8°C
• CAS DataBase Reference: N-BENZOYL-L-ASPARTIC ACID-Beta-METHYL ESTER(CAS DataBase Reference)
• NIST Chemistry Reference: N-BENZOYL-L-ASPARTIC ACID-Beta-METHYL ESTER(39741-26-9)
• EPA Substance Registry System: N-BENZOYL-L-ASPARTIC ACID-Beta-METHYL ESTER(39741-26-9)

Safety Data

• Hazardous Substances Data: 39741-26-9(Hazardous Substances Data)

Usage

General Description

N-BENZOYL-L-ASPARTIC ACID-Beta-METHYL ESTER, also known as N-Boc-L-aspartic acid β-methyl ester, is a chemical compound commonly used in the synthesis of peptide-based drugs and pharmaceuticals. It is an ester derivative of N-Boc-L-aspartic acid, a non-proteinogenic amino acid commonly used as a building block in the synthesis of peptides. This chemical is often utilized as a precursor in the production of various drugs and biologically active molecules, due to its ability to easily undergo chemical transformations. It is also used as a reagent in organic synthesis and as a coupling reagent in peptide synthesis. However, it is important to handle N-BENZOYL-L-ASPARTIC ACID-Beta-METHYL ESTER with caution, as it can be hazardous if not properly handled and stored.

Upstream product

• 2177-62-0 β-methyl L-aspartate 
• 98-88-4 benzoyl chloride 
• 16856-13-6 (+)-β-methyl-L-aspartate hydrochloride 

Downstream Products

• 60272-64-2 2-phenyl-4-methoxycarbonylmethyl-5-oxo-4,5-dihydro-1,3-oxazole 
• 1562416-43-6 C₁₃H₁₅NO₅ 
• 86555-45-5 (2S)-N-benzoyl-L-aspartic acid dimethyl ester 
• 141200-66-0 5-<4-<<2-(5-methyl-2-phenyl-4-oxazolyl)ethyl>sulfonyl>benzyl>thiazolidine-2,4-dione 
• 132451-13-9 N-[4-(2,4-Dioxo-thiazolidin-5-ylmethyl)-phenyl]-N-ethyl-2-(5-methyl-2-phenyl-oxazol-4-yl)-acetamide 
• 132451-26-4 5-[4-[N-Methyl-2-(5-methyl-2-phenyl-4-oxazolyl)acetamido]benzyl]thiazolidine-2,4-dione 
• 132451-20-8 5-<4-<2-(5-methyl-2-phenyl-4-oxazolyl)acetamido>benzyl>thiazolidine-2,4-dione 
• 132451-22-0 5-[4-[2-(5-Methyl-2-phenyl-4-oxazolyl)-ethylthio]benzyl]thiazolidine-2,4-dione 
• 132451-21-9 5-<<4-<<2-(5-methyl-2-phenyl-4-oxazolyl)ethyl>thio>phenyl>methylene>thiazolidine-2,4-dione 
• 132451-34-4 4-[2-(5-methyl-2-phenyl-4-oxazolyl)-ethylthio]benzaldehyde 
• 132451-33-3 4-<2-<(4-bromophenyl)thio>ethyl>-5-methyl-2-phenyloxazole 
• 132451-32-2 2-(5-Methyl-2-phenyl-4-oxazolyl)ethyl Bromide 
• 103788-55-2 2-imino-5-<4-<2-(5-methyl-2-phenyl-4-oxazoyl)ethoxy>benzyl>-4-thiazolidinone 
• 103789-42-0 5-{4-[2-(5-methyl-2-phenyl-4-oxazolyl)ethoxy]benzylidene}-2,4-thiazolidinedione 

Relevant articles and documents

Peptide-catalyzed conversion of racemic oxazol-5(4 H)-ones into enantiomerically enriched α-amino acid derivatives

We report the development and optimization of a tetrapeptide that catalyzes the methanolytic dynamic kinetic resolution of oxazol-5(4H)-ones (azlactones) with high levels of enantioinduction. Oxazolones possessing benzylic-type substituents were found to perform better than others, providing methyl ester products in 88:12 to 98:2 er. The mechanism of this peptide-catalyzed process was investigated through truncation studies and competition experiments. High-field NOESY analysis was performed to elucidate the solution-phase structure of the peptide, and we present a plausible model for catalysis.

Novel Thiazolidine-2,4-diones as Potent Euglycemic Agents

A new series of thiazolidine-2,4-diones was obtained by replacing the ether function of englitazone with various functional groups, i.e., a ketone, alcohol, or olefin moiety.These compounds lower blood glucose levels in the genetically obese and insulin-r