3979-45-1

Basic information

• Product Name: ETHYL 2-CHLORO-3-NITROBENZOATE
• Synonyms: ETHYL 2-CHLORO-3-NITROBENZOATE;2-Chloro-3-nitro-benzoic acid ethyl ester
• CAS NO: 3979-45-1
• Molecular Formula: C₉H₈ClNO₄
• Molecular Weight: 229.62
• Product Categories: Aromatic Esters
• Mol File: 3979-45-1.mol
• Article Data: 3

Chemical Properties

• Appearance: /
• CAS DataBase Reference: ETHYL 2-CHLORO-3-NITROBENZOATE(CAS DataBase Reference)
• NIST Chemistry Reference: ETHYL 2-CHLORO-3-NITROBENZOATE(3979-45-1)
• EPA Substance Registry System: ETHYL 2-CHLORO-3-NITROBENZOATE(3979-45-1)

Safety Data

• Hazardous Substances Data: 3979-45-1(Hazardous Substances Data)

Usage

General Description

ETHYL 2-CHLORO-3-NITROBENZOATE is a chemical compound with the molecular formula C9H8ClNO4. It is a yellow crystalline solid that is commonly used as an intermediate in the synthesis of various pharmaceuticals and agrochemicals. ETHYL 2-CHLORO-3-NITROBENZOATE is known for its strong nitro and ester functionality, making it useful in organic synthesis. It is important to handle this chemical with caution, as it may cause irritation to the skin, eyes, and respiratory system upon contact or inhalation. Additionally, it is flammable and should be stored and handled in a well-ventilated area away from sources of ignition. Overall, ETHYL 2-CHLORO-3-NITROBENZOATE serves as a versatile building block in the production of various important chemical compounds.

Upstream product

• 3970-35-2 2-chloro-3-nitrobezoic acid 
• 64-17-5 ethanol 

Downstream Products

• 145040-37-5 candesartan cilexetil 
• 139481-59-7 candesartan 
• 139481-58-6 ethyl 2-ethoxy-1-[[2'-(1H-tetrazol-5-yl)biphenyl-4-yl]-methyl]benzimidazole-7-carboxylate 
• 170791-09-0 cilexetil trityl candesartan 
• 916891-90-2 ethyl 3-amino-2-(4-bromobenzylamine)-benzoate 
• 854538-88-8 ethyl 1-(4-bromobenzyl)-2-ethoxy-benzimidazole-7-carboxylate 
• 854538-90-2 1-(4-bromobenzyl)-2-ethoxy-benzoimidazole-7-carboxylic acid 
• 1353575-38-8 ethyl 2-chloro-3-(methylsulfonamido)benzoate 
• 1261671-67-3 ethyl 3-amino-2-chlorobenzoate 
• 80568-14-5 5-amino-1-<<2-(diethylamino)ethyl>amino>-4-methylthioxanthenone 
• 80568-13-4 2-<(5-chloro-2-methylphenyl)thio>-3-nitrobenzoic acid 
• 145933-23-9 7-nitro-2-phenyl-1,2-dihydro-3H-indazol-3-one 
• 31775-97-0 7-nitro-indazolin-3-one 

Relevant articles and documents

Biphenyl compound as well as preparation method and medical application thereof

The invention discloses a biphenyl compound as well as a preparation method and medical application thereof, the structure of the biphenyl compound is shown as a formula (I) or a formula (II), and thebiphenyl compound or pharmaceutically acceptable salt, tautomer, meso-isomer, raceme, stereoisomer, metabolite, metabolite precursor, prodrug or solvate thereof is a PD-L1 inhibitor. The compound hasa remarkable inhibiting effect on the interaction of PD-1 and PD-L1 protein, so that the compound can be applied to the preparation of PD-L1 inhibitors and immunomodulator drugs for preventing or treating tumors, autoimmune diseases, organ transplant rejection, infectious diseases and inflammatory diseases.

METHOD FOR OBTAINING BENZIMIDAZOLE DERIVATIVES AND INTERMEDIATES THEREOF

The present invention relates to a method for obtaining benzimizadole derivatives and intermediates thereof, preferably, for obtaining Candesartan and Candesartan cilexetil. Said method allows the benzimizadole derivatives to be obtained with a higher yield.