3979-45-1

Usage

Uses

Used in Pharmaceutical Industry:
ETHYL 2-CHLORO-3-NITROBENZOATE is used as a key intermediate in the synthesis of various pharmaceuticals for its ability to contribute to the formation of complex organic molecules. Its strong nitro and ester functionalities make it a valuable component in the development of new drugs.
Used in Agrochemical Industry:
In the agrochemical sector, ETHYL 2-CHLORO-3-NITROBENZOATE is employed as an intermediate in the production of agrochemicals, such as pesticides and herbicides. Its chemical properties allow for the creation of effective compounds designed to protect crops and enhance agricultural productivity.
Used in Organic Synthesis:
ETHYL 2-CHLORO-3-NITROBENZOATE is utilized as a versatile building block in organic synthesis for its capacity to form a variety of chemical compounds. Its strong functional groups facilitate reactions that lead to the creation of new molecules with diverse applications in various industries.

Upstream product

• 64-17-5 ethanol 
• 3970-35-2 2-chloro-3-nitrobezoic acid 

Downstream Products

• 31775-97-0 7-nitro-indazolin-3-one 
• 145040-37-5 candesartan cilexetil 
• 139481-59-7 candesartan 
• 139481-58-6 ethyl 2-ethoxy-1-[[2'-(1H-tetrazol-5-yl)biphenyl-4-yl]-methyl]benzimidazole-7-carboxylate 
• 170791-09-0 cilexetil trityl candesartan 
• 916891-90-2 ethyl 3-amino-2-(4-bromobenzylamine)-benzoate 
• 854538-88-8 ethyl 1-(4-bromobenzyl)-2-ethoxy-benzimidazole-7-carboxylate 
• 854538-90-2 1-(4-bromobenzyl)-2-ethoxy-benzoimidazole-7-carboxylic acid 
• 1353575-38-8 ethyl 2-chloro-3-(methylsulfonamido)benzoate 
• 1261671-67-3 ethyl 3-amino-2-chlorobenzoate 
• 80568-14-5 5-amino-1-<<2-(diethylamino)ethyl>amino>-4-methylthioxanthenone 
• 80568-13-4 2-<(5-chloro-2-methylphenyl)thio>-3-nitrobenzoic acid 
• 145933-23-9 7-nitro-2-phenyl-1,2-dihydro-3H-indazol-3-one 

Relevant academic research and scientific papers

Biphenyl compound as well as preparation method and medical application thereof

The invention discloses a biphenyl compound as well as a preparation method and medical application thereof, the structure of the biphenyl compound is shown as a formula (I) or a formula (II), and thebiphenyl compound or pharmaceutically acceptable salt, tautomer, meso-isomer, raceme, stereoisomer, metabolite, metabolite precursor, prodrug or solvate thereof is a PD-L1 inhibitor. The compound hasa remarkable inhibiting effect on the interaction of PD-1 and PD-L1 protein, so that the compound can be applied to the preparation of PD-L1 inhibitors and immunomodulator drugs for preventing or treating tumors, autoimmune diseases, organ transplant rejection, infectious diseases and inflammatory diseases.

HETEROARYL COMPOUNDS AND COMPOSITIONS AS PROTEIN KINASE INHIBITORS

The present invention provides compounds of Formula (I): wherein R1, R2, R3, and X are as defined herein. The compounds of Formula (I) and pharmaceutical compositions thereof are useful for the treatment of cancer, and B-

METHOD FOR OBTAINING BENZIMIDAZOLE DERIVATIVES AND INTERMEDIATES THEREOF

The present invention relates to a method for obtaining benzimizadole derivatives and intermediates thereof, preferably, for obtaining Candesartan and Candesartan cilexetil. Said method allows the benzimizadole derivatives to be obtained with a higher yield.