398-46-9Relevant academic research and scientific papers
Synthesis, Biological Activity and Action Mechanism Study of Novel Chalcone Derivatives Containing Malonate
Guo, Tao,Xia, Rongjiao,Liu, Tingting,Peng, Feng,Tang, Xuemei,Zhou, Qing,Luo, Hui,Xue, Wei
, (2020/03/13)
A series of novel chalcone malonate derivatives were synthesized and their antibacterial and antiviral activities were evaluated. All target compounds were characterized by spectral data. The results of antimicrobial bioassay showed that one compound (die
Synthesis and antimicrobial activities of new 4,6-diaryl- 4,5-dihydro-3-hydroxy-2H-indazoles
Amutha, Parasuraman,Nagarajan, Samuthira
experimental part, p. 428 - 432 (2012/06/30)
A series of new 4,6-diaryl-4,5-dihydro-3-hydroxy-2H-indazoles 5a-5k were synthesized by the cyclization of ethyl 2-oxo-4,6-diarylcyclohex-3-ene carboxylates 4a-4k. The compounds were characterized by IR, 1H NMR, 13C NMR, 2D NMR, and elemental analysis. The synthesized compounds were evaluated for in vitro antibacterial and antifungal activities against Staphylococcus aureus, Escherichia coli, Salmonella typhimurium, Pseudomonas aeruginosa, Candida albicans, Aspergillus niger, Aspergillus flavus, and Rhizopus sp. Most of the compounds exhibited good activity against the tested organisms. Copyright
Anti-bacterial and anti-leishmanial studies of 4, 6-diarylpyrimidin-2- amines
Bukhari, Mujahid Hussain,Siddiqui, Hamid Latif,Ashraf, Chaudhary Muhammad,Hussain, Tanvir
scheme or table, p. 720 - 725 (2012/06/18)
Seven new chalcones along with nine already reported ones were synthesized from aryl aldehydes and substituted acetophenones by Claisen-Schmidt condensation. Each chalcone was treated with guanidine hydrochloride followed by oxidation with H2O
Tetrachlorosilane-zinc chloride as a new potent binary reagent for one-pot, three-component synthesis of mannich-type products
Badawy, Doria S.,Abdel-Galil, Ebrahim,Kandeel, Ezzat M.,Basyouni, Wahid M.,Khatab, Tamer K.
experimental part, p. 2799 - 2812 (2010/04/03)
A combination of tetrachlorosilane and zinc chloride in dichloromethane as an efficient and ambient binary reagent to promote a one-pot amidoalkylation reaction of enolizable ketones, aromatic aldehydes with acetonitriles, or benzonitrile have been develo
Atom-efficient, solvent-free, green synthesis of chalcones by grinding
Rateb, Nora M.,Zohdi, Hussein F.
experimental part, p. 2789 - 2794 (2009/12/06)
An improved Claisen-Schmidt condensation reaction of methyl ketones and aromatic aldehydes can be achieved by grinding at room temperature in the absence of solvents. This process is simple, efficient, economical, and environmentally benign compared to classical reactions.
