398117-91-4Relevant articles and documents
Copper-Catalyzed Annulative Coupling of S,S-Disubstituted Enones with Diazo Compounds to Access Highly Functionalized Thiophene Derivatives
He, Yuan,Lou, Jiang,Wu, Ping,Yu, Zhengkun,Zhou, Yong-Gui
, (2020/01/31)
An efficient protocol toward fully substituted thiophenes and thieno[2,3-b]thiophenes has been developed through CuCl2-catalyzed annulative coupling of S,S-disubstituted enones with diazo compounds under mild conditions. Tetrasubstituted thiophenes and thieno[2,3-b]thiophenes were efficiently accessed by variation of the feed ratio of the reactants in good to excellent yields, respectively. The synthetic methodology has demonstrated the potential for the construction of diverse thiophene derivatives.
Efficient one pot preparation of variously substituted thieno[2,3-b]thiophene
Comel,Kirsch
, p. 1167 - 1171 (2007/10/03)
An efficient one pot access to variously substituted thieno[2,3-b]thiophene is described. The title compounds were obtained from 1,3-dicarbonyl or equivalent compounds, carbon disulfide and halomethyl derivatives in good to high yields and fully characterized.