398137-91-2Relevant academic research and scientific papers
Development of a stepwise [3 + 3] annelation to functionalized piperidines
Goodenoug, Katharine M.,Raubo, Piotr,Harrity, Joseph P. A.
, p. 2993 - 2996 (2007/10/03)
(Chemical Equation Presented) A stepwise formal [3 + 3] cycloaddition sequence via a Grignard addition-cyclization reaction leads to a much improved piperidine synthesis. This methodology provides improved flexibility in both the aziridine substrate and T
Development of a [3+3] cycloaddition strategy toward functionalized piperidines
Hedley, Simon J.,Moran, Wesley J.,Price, David A.,Harrity, Joseph P. A.
, p. 4286 - 4292 (2007/10/03)
This paper describes a novel route to functionalized piperidines via a formal [3+3] cycloaddition reaction of activated aziridines and palladium-trimethylenemethane (Pd-TMM) complexes. The cycloaddition reaction generally proceeds enantiospecifically with
Synthesis of functionalised piperidines through a [3+3] cycloaddition strategy
Hedley,Moran,Prenzel,Price,Harrity
, p. 1596 - 1598 (2007/10/03)
A novel approach to functionalised piperidines is described through a [3+3] cycloaddition reaction of aziridines with Pd-trimethylenemethane complexes. Importantly, the employment of enantiomerically pure aziridines (prepared in three steps from the appro
