71535-50-7

Basic information

• Product Name: Aziridine, 1-[(4-methylphenyl)sulfonyl]-2-(phenylmethyl)-
• Synonyms: Aziridine,1-[(4-methylphenyl)sulfonyl]-2-(phenylmethyl);2-benzyl-1-[(4-methylphenyl)sulfonyl]aziridine
• CAS NO: 71535-50-7
• Molecular Formula: C16H17NO2S
• Molecular Weight: 287.382
• Mol File: 71535-50-7.mol
• Article Data: 43

Chemical Properties

• CAS DataBase Reference: Aziridine, 1-[(4-methylphenyl)sulfonyl]-2-(phenylmethyl)-(CAS DataBase Reference)
• NIST Chemistry Reference: Aziridine, 1-[(4-methylphenyl)sulfonyl]-2-(phenylmethyl)-(71535-50-7)
• EPA Substance Registry System: Aziridine, 1-[(4-methylphenyl)sulfonyl]-2-(phenylmethyl)-(71535-50-7)

Safety Data

• Hazardous Substances Data: 71535-50-7(Hazardous Substances Data)

Upstream product

• 82495-70-3 (2S)-2-p-toluenesulfonamido-3-phenylpropanol 
• 3182-95-4 L-Phenylalaninol 
• 98-59-9 p-toluenesulfonyl chloride 
• 63-91-2 L-phenylalanine 
• 13505-32-3 N-tosyl-(S)-phenylalanine 
• 300-57-2 allylbenzene 
• 55962-05-5 4-methyl-N-[(E)-phenyl-λ³-iodanylidene]benzenesulfonamide 
• 186581-53-3 diazomethane 
• 51608-60-7 N-(benzylidene)-p-methylbenzenesulfonamide 
• 24395-14-0 N-(p-tolylsulfonyl)-2-phenylaziridine 
• 717918-03-1 4-methyl-N-(2-phenylethylidene)benzenesulfonamide 
• 941-55-9 4-toluenesulfonyl azide 
• 127-65-1 chloroamine-T 
• 1593-60-8 p-toluenesulfonylhydroxylamine 

Downstream Products

• 74555-65-0 2,2-bis(ethylthio)-4S-(p-toluenesulphonamido)-5-phenylpentanoic acid 
• 154047-41-3 (S)-1-(2-trimethylsilyl-1,3-dithian-2-yl)-2-(4-methylbenzenesulfonamido)-3-phenylpropane 
• 203452-43-1 (2S,4S)-2-Benzyl-6-methyl-1,4-bis-(toluene-4-sulfonyl)-1,2,3,4-tetrahydro-pyridine 
• 203207-78-7 N-[(S)-1-Benzyl-5,5-dimethoxy-3-(toluene-4-sulfonyl)-pentyl]-4-methyl-benzenesulfonamide 
• 13906-90-6 2-benzylaziridine 
• 313699-07-9 (1R,3S,4E,2'R)-N-{3-(benzo[1,3]dioxol-5-yl)-1-benzyl-4-[2'-(methoxymethyl)pyrrolidin-1'-ylimino]-butyl}-4-methylbenzenesulfonamide 
• 398137-91-2 (R)-2-benzyl-5-methylene-1-(toluene-4-sulfonyl)-piperidine 
• 362495-79-2 [2S,4R,1'S,2'S]-(+)-N,2-dimethyl-5-phenyl-N-(2'-phenyl-2'-hydroxy-1'-methylethyl)-4-(p-toluenesulfonylamino)pentanamide 
• 406937-88-0 N-[(1S)-2-(1-benzothien-3-yl)-1-benzylethyl]-4-methylbenzenesulfonamide 
• 90786-30-4 N-(2-bromo-1-benzylethyl)-4-methylbenzenesulfonamide 
• 925425-91-8 N,N'-[(2S,2'S)-diselanediylbis(1-phenylpropane-3,2-diyl)]bis(4-methylbenzenesulfonamide) 

Relevant articles and documents

Ni-Catalyzed Carboxylation of Aziridines en Route to β-Amino Acids

A Ni-catalyzed reductive carboxylation of N-substituted aziridines with CO2 at atmospheric pressure is disclosed. The protocol is characterized by its mild conditions, experimental ease, and exquisite chemo- and regioselectivity pattern, thus unlocking a new catalytic blueprint to access β-amino acids, important building blocks with considerable potential as peptidomimetics.

Synthesis and hetero-Diels-Alder reactions of enantiomerically pure dihydro-1: H -azepines

Thermolysis of enantiomerically pure 3-substituted 7,7-dihalo-2-azabicyclo[4.1.0]heptanes in the presence of K2CO3 gives in good yields 2-alkyl-6-halo-1-tosyl-2,3-dihydro-1H-azepines. These undergo highly stereoselective [4+2] cycloaddition reactions with heterodienophiles and arylation/alkenylation under Suzuki conditions.

Carbon Isotope Labeling Strategy for β-Amino Acid Derivatives via Carbonylation of Azanickellacycles

A series of 4-membered azametallacycles have been prepared by the oxidative addition of Ni(0) with aziridines. Stoichiometric 13C-labeled carbon monoxide could be efficiently incorporated via Ni-C bond insertion to generate air stable and isola