398142-85-3

Basic information

• Product Name: (+/-)-acetic acid [3-methoxy-5-(2-trimethylsilanylethoxymethoxy)phenyl](2-phenyl[1,3]dithian-2-yl)methyl ester
• Synonyms: (+/-)-acetic acid [3-methoxy-5-(2-trimethylsilanylethoxymethoxy)phenyl](2-phenyl[1,3]dithian-2-yl)methyl ester
• CAS NO: 398142-85-3
• Molecular Weight: 520.786
• Mol File: 398142-85-3.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: (+/-)-acetic acid [3-methoxy-5-(2-trimethylsilanylethoxymethoxy)phenyl](2-phenyl[1,3]dithian-2-yl)methyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: (+/-)-acetic acid [3-methoxy-5-(2-trimethylsilanylethoxymethoxy)phenyl](2-phenyl[1,3]dithian-2-yl)methyl ester(398142-85-3)
• EPA Substance Registry System: (+/-)-acetic acid [3-methoxy-5-(2-trimethylsilanylethoxymethoxy)phenyl](2-phenyl[1,3]dithian-2-yl)methyl ester(398142-85-3)

Safety Data

• Hazardous Substances Data: 398142-85-3(Hazardous Substances Data)

Upstream product

• 5425-44-5 2-Phenyl-[1,3]dithiane 
• 75-36-5 acetyl chloride 
• 398142-83-1 3-methoxy-5-(2-trimethylsilanylethoxymethoxy)benzaldehyde 
• 76513-69-4 (2-trimethylethylsilylethoxy)methyl chloride 
• 57179-35-8 3-hydroxy-5-methoxybenzaldehyde 

Downstream Products

• 398142-90-0 2-(9H-fluoren-9-ylmethoxycarbonylamino)-3-methylbutyric acid [3-(3-tert-butoxycarbonylpropoxy)-5-methoxyphenyl](2-phenyl[1,3]dithian-2-yl)methyl ester 
• 398142-91-1 2-(9H-fluoren-9-ylmethoxycarbonylamino)-3-methylbutyric acid [3-(3-carboxypropoxy)-5-methoxyphenyl](2-phenyl[1,3]dithian-2-yl)methyl ester 
• 398142-87-5 (+/-)-1-acetoxy-1-[3-(4-carbotertbutyloxy)-1-butyloxy-5-methoxyphenyl]-2-phenyl-2-(1,3-dithian-2-yl)ethane 
• 398142-81-9 (+/-)-1-hydroxy-1-[3-(4-carbotertbutyloxy)-1-butyloxy-5-methoxyphenyl]-2-phenyl-2-(1,3-dithian-2-yl)ethane 
• 398142-77-3 (+/-)-4-{3-[hydroxy(2-phenyl[1,3]dithian-2-yl)methyl]-5-methoxyphenoxy}butyric acid 
• 398142-86-4 (+/-)-acetic acid (3-hydroxy-5-methoxyphenyl)(2-phenyl[1,3]dithian-2-yl)methyl ester 

Relevant articles and documents

Practical synthesis of a dithiane-protected 3′,5′-dialkoxybenzoin photolabile safety-catch linker for solid-phase organic synthesis

The solution-phase preparation of the 3′,5′-dialkoxybenzoin photolabile safety-catch linker 16 is described. Pivotal to this convenient synthesis is the selection of appropriate orthogonal protecting groups for the alkoxy functionalities present. The new linker can be readily loaded onto any standard amine-terminating resin under peptide-coupling conditions, without the need to protect the secondary alcohol functionality, and subsequently loaded with substrate. Alternatively, the loading efficiency of sterically hindered substrates can be enhanced by preloading the semiprotected linker variant 10 in solution prior to immobilization onto the resin. This second generation of benzoin photolabile safety-catch linkers provides greater control of both linker loading and resin attachment and should prove to be a more versatile and convenient form of the linker.