39832-48-9

Usage

InChI:InChI=1/C9H16N2O2S/c1-7(2)11-5-8(12)6-13-9-10-3-4-14-9/h3-4,7-8,11-12H,5-6H2,1-2H3

Upstream product

• 3034-53-5 2-bromo-1,3-thiazole 
• 556-52-5 oxiranyl-methanol 
• 75-31-0 isopropylamine 
• 39832-47-8 1-(thiazol-2-yloxy)-2,3-epoxypropane 
• 39832-49-0 2-(2,2-dimethyl-[1,3]dioxolan-4-ylmethoxy)-thiazole 
• 39832-45-6 3-thiazol-2-yloxy-propane-1,2-diol 

Relevant academic research and scientific papers

THIAZOLE CARDIOVASCULAR AGENTS

1-Amino-3-2-thiazoloxy!-2-propanol and substituted 1-amino derivatives thereof; 3-2-thiazoloxy!-1,2-epoxypropane 5-thiazol-2-oxymethylene!-oxazolidine and/or N-substituted and/or 2-substituted oxazolidine, derivatives thereof and methods of preparing such compounds. The above 1-amino-3-2-thiazoloxy!-2-propanol and derivatives exhibit . beta.-adrenergic stimulating cardiovascular activity and are useful for the treatment of abnormal heart conditions in mammals. The above 3-2-thiazoloxy!-1,2-epoxypropane and derivatives are useful as intermediates for the aforementioned cardiovascular agents. The 5-thiazol-2-oxymethylene!-oxazolidine and derivatives are intermediates for aforementioned cardiovascular agents. The 1-amino-3-2-thiazoloxy!-2-propanol and derivatives can be prepared by base or acid hydrolysis of the corresponding 5-thiazol-2-oxymethylene!-oxazolidine or derivatives; or by treatment of the corresponding 3-2-thiazoloxy!-2,3-epoxypropane or derivative with the desired amine or amino-derivative.