39856-57-0

Basic information

• Product Name: 2,6-Dibromopyridin-3-amine
• Synonyms: 2,6-DIBROMOPYRIDIN-3-AMINE;2,6-DIBROMO-PYRIDIN-3-YLAMINE;2,6-DIBROMO-3-PYRIDINAMINE;3-AMINO-2,6-DIBROMOPYRIDINE;3-AMINO-2,6-DIBROMOPYRIDINE(2-AMINO-5-NITRO-4-METHYLPYRIDINE);2,6-Dibromo-4-methylpyridin-3-amine ,97％;3-Amino-2,6-dibromopyridine ,98%;2,6-Dibromo-3-pyridinamine 3-Amino-2,6-dibromopyridine
• CAS NO: 39856-57-0
• Molecular Formula: C₅H₄Br₂N₂
• Molecular Weight: 251.91
• EINECS: 3985-657-0
• Product Categories: Amines;blocks;Bromides;Pyridines;Heterocycles;Others chemical reagents;Building Blocks;C5;Chemical Synthesis;Heterocyclic Building Blocks;New Products for Chemical Synthesis;Heterocycle-Pyridine series;amine| alkyl bromide
• Mol File: 39856-57-0.mol
• Article Data: 2

Chemical Properties

• Melting Point: 214-218C
• Boiling Point: 327.7 °C at 760 mmHg
• Flash Point: 152 °C
• Appearance: /
• Density: 2.147 g/cm³
• Vapor Pressure: 0.000198mmHg at 25°C
• Refractive Index: 1.672
• Storage Temp.: Keep in dark place,Sealed in dry,Room Temperature
• PKA: -0.19±0.10(Predicted)
• CAS DataBase Reference: 2,6-Dibromopyridin-3-amine(CAS DataBase Reference)
• NIST Chemistry Reference: 2,6-Dibromopyridin-3-amine(39856-57-0)
• EPA Substance Registry System: 2,6-Dibromopyridin-3-amine(39856-57-0)

Safety Data

• Hazard Codes: Xi,T
• Statements: 36/37/38-41-25
• Safety Statements: 26-36-45-39-36/37/39
• RIDADR: 2811
• HazardClass: 6.1
• PackingGroup: Ⅲ
• Hazardous Substances Data: 39856-57-0(Hazardous Substances Data)

Usage

Chemical Properties

Brown powder

InChI:InChI=1/C5H4Br2N2/c6-4-2-1-3(8)5(7)9-4/h1-2H,8H2

Upstream product

• 462-08-8 pyridin-3-ylamine 
• 1657-32-5 3-aminopyridine-N-oxide 
• 98-92-0 nicotinamide 

Downstream Products

• 1133434-13-5 2,6-Dibromopyridine-3-diazonium Tetrafluoroborate 
• 1112982-76-9 N-(5-bromothiazolo[5,4-b]pyridin-2-yl)acetamide 
• 1402004-16-3 7-(4-methyl-1H-imidazol-1-yl)-3,4-dihydropyrido[2,1-c]-[1,4]oxazine-1,6-dione 
• 1262197-81-8 methyl 6-methoxy-5-(4-methyl-1H-imidazol-1-yl)pyridine-2-carboxylate 

Relevant articles and documents

Mild regioselective halogenation of activated pyridines with N-bromosuccinimide

Regioselective mono and dihalogenations of amino, hydroxy and methoxy pyridines (2-, 3-, and 4-substituted) as well as 2,6-dimethoxy pyridine with N-bromosuccinimide in different solvents have been studied. Reactivity of the substrates decreases in the order amino>hydroxy>methoxy and regioselectivity depends on the position of the substituent (2-substituted > 3-substituted). In most of the cases we obtained monobrominated derivatives regioselectively and in high yields. Hydroxy and amino pyridines can also be dibrominated in almost quantitative yield with 2 equivalents of NBS.