618398-67-7Relevant academic research and scientific papers
Synthesis of 2-pyridones as tissue factor VIIa inhibitors
Parlow, John J.,South, Michael S.
, p. 7695 - 7701 (2007/10/03)
2-Pyridones were prepared from 2,6-dibromopyridine via a multi-step synthesis. A variety of chemical transformations, including regioselective nucleophilic addition and selective nitrogen alkylation, afforded the penultimate intermediate 9. A combination
Design, Synthesis, and Crystal Structure of Selective 2-Pyridone Tissue Factor VIIa Inhibitors
Parlow, John J.,Kurumbail, Ravi G.,Stegeman, Roderick A.,Stevens, Anna M.,Stallings, William C.,South, Michael S.
, p. 4696 - 4701 (2007/10/03)
Targeted 2-pyridones were selected as tissue Factor VIIa inhibitors and prepared from 2,6-dibromopyridine via a multistep synthesis. A variety of chemical transformations, including regioselective nucleophilic addition, selective nitrogen alkylation, and
