39886-78-7

Basic information

• Product Name: 2-Butanone, 4-[3-methoxy-4-(phenylmethoxy)phenyl]-
• CAS NO: 39886-78-7
• Molecular Formula: C18H20O3
• Molecular Weight: 284.355
• Mol File: 39886-78-7.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: 2-Butanone, 4-[3-methoxy-4-(phenylmethoxy)phenyl]-(CAS DataBase Reference)
• NIST Chemistry Reference: 2-Butanone, 4-[3-methoxy-4-(phenylmethoxy)phenyl]-(39886-78-7)
• EPA Substance Registry System: 2-Butanone, 4-[3-methoxy-4-(phenylmethoxy)phenyl]-(39886-78-7)

Safety Data

• Hazardous Substances Data: 39886-78-7(Hazardous Substances Data)

Upstream product

• 72724-00-6 1-(benzyloxy)-4-(bromomethyl)-2-methoxybenzene 
• 75335-47-6 4-(4′-benzyloxy-3′-methoxyphenyl)-3-buten-2-one 
• 2426-87-1 3-methoxy-4-(phenylmethoxy)benzaldehyde 
• 100-39-0 benzyl bromide 
• 13483-31-3 Acetone dimethylhydrazone 
• 121-33-5 vanillin 
• 100-44-7 benzyl chloride 
• 33693-48-0 4-benzyloxy-3-methoxybenzyl alcohol 

Downstream Products

• 39886-76-5 [6]-gingerol 
• 72749-01-0 (R)-5-hydroxy-1-(4-hydroxy-3-methoxyphenyl)decan-3-one 
• 122-48-5 4-(4-hydroxy-3-methoxyphenyl)-2-butanone 
• 39886-80-1 1-(4-benzyloxy-3-methoxyphenyl)-5-hydroxydecan-3-one 

Relevant articles and documents

MnO2as a terminal oxidant in Wacker oxidation of homoallyl alcohols and terminal olefins

Efficient and mild reaction conditions for Wacker-type oxidation of terminal olefins of less explored homoallyl alcohols to β-hydroxy-methyl ketones have been developed by using a Pd(ii) catalyst and MnO2 as a co-oxidant. The method involves mild reaction conditions and shows good functional group compatibility along with high regio- and chemoselectivity. While our earlier system of PdCl2/CrO3/HCl produced α,β-unsaturated ketones from homoallyl alcohols, the present method provided orthogonally the β-hydroxy-methyl ketones. No overoxidation or elimination of benzylic and/or β-hydroxy groups was observed. The method could be extended to the oxidation of simple terminal olefins as well, to methyl ketones, displaying its versatility. An application to the regioselective synthesis of gingerol is demonstrated.

Enantioselective synthesis of (-)-(R) and (+)-(S)-[6]-Gingerol - pungent principle of ginger

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