39969-28-3

Usage

Uses

Used in Organic Synthesis:
1-(4-METHOXYPHENYL)-2-(4-N-PROPYLPHENYL)ACETYLENE is utilized as a key intermediate in organic synthesis for its ability to form complex molecular structures. Its unique structure and reactivity make it a valuable component in the synthesis of a variety of compounds.
Used in Pharmaceutical Production:
In the pharmaceutical industry, 1-(4-METHOXYPHENYL)-2-(4-N-PROPYLPHENYL)ACETYLENE is used as a building block for the development of new drugs. Its distinctive structure contributes to the creation of molecules with potential therapeutic properties.
Used in Agrochemical Development:
1-(4-METHOXYPHENYL)-2-(4-N-PROPYLPHENYL)ACETYLENE also serves as a precursor in the agrochemical sector, where it is employed in the synthesis of compounds with pesticidal or herbicidal activity, contributing to the development of more effective crop protection agents.
Used in Materials Science:
Within materials science, 1-(4-METHOXYPHENYL)-2-(4-N-PROPYLPHENYL)ACETYLENE has potential applications in the development of new materials with unique properties, such as high thermal stability or specific electronic characteristics.
Used as a Research Tool in Organic Chemistry:
1-(4-METHOXYPHENYL)-2-(4-N-PROPYLPHENYL)ACETYLENE is also used as a research tool in organic chemistry, where it aids scientists in understanding reaction mechanisms and exploring new synthetic pathways.

InChI:InChI=1/C20H22O/c1-3-4-5-6-17-7-9-18(10-8-17)11-12-19-13-15-20(21-2)16-14-19/h7-10,13-16H,3-6H2,1-2H3

Upstream product

• 5720-07-0 4-methoxyphenylboronic acid 
• 79887-10-8 1-ethynyl-4-(n-pentyl)benzene 
• 696-62-8 para-iodoanisole 
• 100-66-3 methoxybenzene 

Downstream Products

• 7465-87-4 N-benzyl-4-methoxybenzamide 

Relevant academic research and scientific papers

2,2-Diazido-1,2-diarylethanones: Synthesis and Reactivity with Primary Amines

We describe the synthesis and reactivity of a new class of diazidated compounds: the 2,2-diazido-1,2-diarylethanones. The diazides are easily accessible from 1,2-diarylethanones through a mild and simple protocol for the direct oxidative diazidation, using iodine and sodium azide in DMSO at room temperature. In studies towards their reactivity with amine nucleophiles under basic conditions, the diazides are shown to undergo a controlled fragmentation reaction that provides a straightforward access to the corresponding amides. In stark contrast to our previous results on the amine-triggered fragmentation of diazidated compounds, aromatic nitriles are found to be by-products of synthetic value. The net reaction consisting of diazidation and subsequent fragmentation, thus, provides a simple way to convert 1,2-diarylethanones into both aromatic amides and nitriles.

Thiosemicarbazone salicylaldiminato palladium(II)-catalyzed alkynylation couplings between arylboronic acids and alkynes or alkynyl carboxylic acids

An efficient catalytic system has been developed for the synthesis of unsymmetrical substituted alkynes via the thiosemicarbazone salicylaldiminato palladium(II)-catalyzed alkynylation couplings between arylboronic acids and alkynes or alkynyl carboxylic acids under mild conditions.

Cyclopalladated ferrocenylimines: efficient catalysts for homocoupling and Sonogashira reaction of terminal alkynes

A novel pathway for homocoupling of terminal alkynes has been described using cyclopalladated ferrocenylimine 1 or 2/CuI as catalyst in the air. This catalytic system could tolerate several functional groups. The palladacycle 2 in the presence of n-Bu4NBr as an additive could be applied to Sonogashira cross-coupling reaction of aryl iodides, aryl bromides, and some activated aryl chlorides with terminal alkynes under amine- and copper-free conditions, mostly to give moderate to excellent yields.

One-pot preparation of arylalkynes by a tandem catalytic iodination of arenes and palladium-catalyzed coupling of iodoarenes with terminal alkynes

Iodination of activated arenes by air-oxidation is carried out in the presence of catalytic bismuth salts at room temperature. Subsequently, the formed iodoarenes react with terminal alkynes to give arylalkynes under a selected palladium-catalyzed coupling condition in the same pot.