39974-35-1

Basic information

• Product Name: 2-chloro-1-nitro-3-(trifluoromethyl)benzene
• Synonyms: 2-chloro-1-nitro-3-(trifluoromethyl)benzene;2-Chloro-3-trifluoromethyl-1-nitrobenzene;1-Chloro-2-nitro-6-(trifluoroMethyl)benzene;2-Chloro-3-nitrobenzotrifluoride;Benzene,2-chloro-1-nitro-3-(trifluoromethyl)-
• CAS NO: 39974-35-1
• Molecular Formula: C₇H₃ClF₃NO₂
• Molecular Weight: 225.5524296
• EINECS: 254-724-9
• Mol File: 39974-35-1.mol
• Article Data: 2

Chemical Properties

• Melting Point: 25-30℃
• Boiling Point: 234.6°Cat760mmHg
• Flash Point: >110°(230°F)
• Appearance: /Solid
• Density: 1.537g/cm³
• Vapor Pressure: 0.0803mmHg at 25°C
• Refractive Index: 1.493
• Storage Temp.: 2-8°C
• CAS DataBase Reference: 2-chloro-1-nitro-3-(trifluoromethyl)benzene(CAS DataBase Reference)
• NIST Chemistry Reference: 2-chloro-1-nitro-3-(trifluoromethyl)benzene(39974-35-1)
• EPA Substance Registry System: 2-chloro-1-nitro-3-(trifluoromethyl)benzene(39974-35-1)

Safety Data

• WGK Germany: 3
• Hazardous Substances Data: 39974-35-1(Hazardous Substances Data)

Usage

Uses

2-Chloro-1-nitro-3-(trifluoromethyl)benzene is used in the synthesis of highly potent and orally effective Inhibitors of FABP4 for anti-inflammation.

InChI:InChI=1/C7H3ClF3NO2/c8-6-4(7(9,10)11)2-1-3-5(6)12(13)14/h1-3H

Upstream product

• 88-16-4 1-chloro-2-(trifluoromethyl)benzene 
• 3970-35-2 2-chloro-3-nitrobezoic acid 

Downstream Products

• 1369770-12-6 2-(trifluoromethyl )-N-methyl-6-nitroaniline 
• 924647-38-1 1-(2,2-difluoroethoxy)-2-(propylsulphanyl)-3-(trifluoromethyl)benzene 
• 865352-01-8 2-(2',2'-difluoroethoxy)-6-trifluoromethylbenzene-1-sulfonyl chloride 
• 24821-17-8 2-Nitro-6-(trifluoromethyl)aniline 

Relevant articles and documents

Preparation and characterization of diazenyl quinolin-8-ol with trifluoromethyl substituents

The synthesis and properties of new monoazo dyes derived from the diazonium salts of 2-trifluoromethyl phenylamine and 4-chloro-3-trifluoromethyl phenylamine are considered.