3999-06-2 Usage
Uses
Used in Medicinal Chemistry and Pharmaceuticals:
Imidazo[1,2-a]pyridin-2(3H)-one is utilized as a key component in drug discovery and development due to its potential therapeutic effects on various diseases and conditions. Its versatile chemical structure allows for the design and synthesis of novel compounds with improved pharmacological properties.
Used in Materials Science:
Imidazo[1,2-a]pyridin-2(3H)-one is employed as a building block in the development of new materials with unique properties. Its incorporation into material compositions can lead to advancements in various applications, such as sensors, catalysts, and other specialized materials.
Used as a Chemical Intermediate in Organic Synthesis:
Imidazo[1,2-a]pyridin-2(3H)-one serves as an essential intermediate in the synthesis of complex organic compounds. Its presence in reaction pathways can facilitate the production of target molecules with specific biological activities or material properties, contributing to the advancement of organic chemistry and its applications.
Check Digit Verification of cas no
The CAS Registry Mumber 3999-06-2 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 3,9,9 and 9 respectively; the second part has 2 digits, 0 and 6 respectively.
Calculate Digit Verification of CAS Registry Number 3999-06:
(6*3)+(5*9)+(4*9)+(3*9)+(2*0)+(1*6)=132
132 % 10 = 2
So 3999-06-2 is a valid CAS Registry Number.
3999-06-2Relevant academic research and scientific papers
KOH-mediated intramolecular amidation and sulfenylation: A direct approach to access 3-(arylthio)imidazo[1,2-a]pyridin-2-ols
Pandey, Khima,Shinde, Vikki N.,Rangan, Krishnan,Kumar, Anil
, (2020/08/24)
A simple and facile method for the synthesis of 3-(arylthio)imidazo[1,2-a]pyridin-2-ols has been developed by a KOH-mediated reaction of 2-aminopyridinium bromides with aryl thiols. The method afforded a wide range of 3-(arylthio)imidazo[1,2-a]pyridin-2-ols in moderate to excellent (56–95%) yields with excellent functional group tolerance. Synthetic utility of the protocol was demonstrated by gram-scale reaction and preparation of 2-aryl-3-(p-tolylthio)imidazo[1,2-a]pyridines from 3-(p-tolylthio)imidazo[1,2-a]pyridin-2-ol.
Metal-free synthesis of pyridin-2-yl ureas from 2-aminopyridinium salts
Saroj,Patel, Om P.S.,Rangan, Krishnan,Kumar, Anil
, (2019/07/23)
An unprecedented base promoted domino approach has been developed for the synthesis of pyridin-2-yl urea derivatives via the reaction of 2-aminopyridinium salts and arylamines. The developed strategy tolerated a wide range of functional groups and afforded pyridin-2-yl ureas in moderate to good yields. The reaction was postulated to involve tandem cyclization, intermolecular nucleophilic addition, ring opening, and demethylation.
