400009-34-9Relevant articles and documents
An aldol-based approach to the synthesis of the antibiotic anisomycin
Hulme, Alison N.,Rosser, Edward M.
, p. 265 - 267 (2007/10/03)
Chemical equation presented A new approach to the synthesis of the antibiotic anisomycin is reported that relies upon a key aldol disconnection. The glycolate aldol coupling proceeds in 75% yield and with >95% diastereoselectivity, which allows the 13-step synthesis to proceed in 35% overall yield.