40040-95-7

Upstream product

• 40040-94-6 2-phenyl-5H-chromeno[3,4-c]pyridin-5-ol 
• 1381807-07-3 2-phenyl-3-tosyl-4,4a-dihydro-3H-chromeno[3,4-c]pyridin-5(10bH)-one 
• 644-78-0 2-hydroxychalcone 
• 90-02-8 salicylaldehyde 
• 98-86-2 acetophenone 
• 108-95-2 phenol 
• 1076-38-6 4-hydroxy[1]benzopyran-2-one 
• 50329-91-4 4-chloro-3-formylcoumarin 
• 107-06-2 1,2-dichloro-ethane 

Relevant academic research and scientific papers

Diversified construction of chromeno[3,4-c]pyridin-5-one and benzo[c]chromen-6-one derivatives by domino reaction of 4-Alkynyl-2-oxo-2H- chromene-3-carbaldehydes

Silver-catalyzed three-component, tandem reactions of 4-alkynyl-2-oxo-2H- chromene-3-carbaldehydes, amines and various nucleophiles result in the formation of highly functionalized chromeno[3,4-c]pyridin-5-ones in high yields. Gold-catalyzed [4+2] cycloadditions of 4-alkynyl-2-oxo-2H-chromene-3- carbaldehydes with alkynes or alkenes have also been achieved to afford benzo[c]chromen-6-ones efficiently.

Enantioselective intramolecular formal [2 + 4] annulation of acrylates and α,β-unsaturated imines catalyzed by amino acid derived phosphines

The first chiral phosphine-catalyzed activation of acrylates for intramolecular formal [2 + 4] reactions with unsaturated imines is described. The catalytic reactions afford N-heterocycles with exceptionally high diastereo- and enantioselectivities. The [2 + 4] products are amenable for further transformations to useful molecules such as chiral piperidines and multicyclic structures.