40060-76-2

Basic information

• Product Name: (±)-phenyl(1H-tetrazol-5-yl)methanol
• Synonyms: (±)-phenyl(1H-tetrazol-5-yl)methanol
• CAS NO: 40060-76-2
• Molecular Weight: 176.178
• Mol File: 40060-76-2.mol
• Article Data: 6

Chemical Properties

• CAS DataBase Reference: (±)-phenyl(1H-tetrazol-5-yl)methanol(CAS DataBase Reference)
• NIST Chemistry Reference: (±)-phenyl(1H-tetrazol-5-yl)methanol(40060-76-2)
• EPA Substance Registry System: (±)-phenyl(1H-tetrazol-5-yl)methanol(40060-76-2)

Safety Data

• Hazardous Substances Data: 40060-76-2(Hazardous Substances Data)

Upstream product

• 119718-87-5 cyano(phenyl)methyl acetate 
• 127843-38-3 4-Tetrazol-2-ylmethyl-morpholine 
• 100-52-7 benzaldehyde 
• 532-28-5 (RS)-mandelonitrile 
• 208122-80-9 (1-Benzyloxymethyl-1H-tetrazol-5-yl)-phenyl-methanol 
• 164589-82-6 1-(1-benzyl-1H-tetrazol-5-yl)(phenyl)methanol 

Downstream Products

• 132778-86-0 1,2-diphenyl-1,2-bis-(1H-tetrazol-5-yl)-ethane-1,2-diol 
• 43134-03-8 diphenyl(1H-tetrazol-5-yl)methanol 
• 18489-25-3 5-benzyl-1H-tetrazole 
• 14506-41-3 phenyl(1H-tetrazol-5-yl)methanone 

Relevant articles and documents

N-Morpholinomethyl-5-lithiotetrazole: A Reagent for the One-Pot Synthesis of 5-(1-Hydroxyalkyl)tetrazoles

An efficient, one-pot method for the preparation of 5-(1-hydroxyalkyl)tetrazoles is reported. N-Morpholinomethyl-5-lithiotetrazole, generated by the deprotonation of 4-(N-tetrazolylmethyl)morpholine with LiHMDS, undergoes addition to ketones and aldehydes (both aromatic and aliphatic) to form 5-(1-hydroxyalkyl)tetrazoles in a high yield, after acidic workup. The reported protocol displays a broad substrate scope and functional group tolerance, avoids the use of cyanide- or azide-based reagents, and provides access to sterically congested and unsaturated tetrazoles, which are difficult to access by other means.

Microwave Synthesis of 5-Substituted 1 H-Tetrazoles Catalyzed by Bismuth Chloride in Water

(Chemical Equation Presented). Bismuth chloride was used to catalyze the [2 + 3] cycloaddition between sodium azide with aryl nitriles, aliphatic nitriles, and vinyl nitriles. A number of 5-substituted 1H-tetrazoles were synthesized in water or isopropano

Homologation of 1-(benzyloxymethyl)-1H-tetrazole via lithiation

Lithiation of 1-(Benzyloxymethyl)-1H-tetrazoIe, prepared by alkylation of 1H-tetrazole with benzyl chloromethyl ether, followed by treatement with a variety of electrophiles afforded its homologation products. Hydrogenation or acid hydrolysis gave the corresponding free tetrazoles.