400652-45-1

Basic information

• Product Name: TERT-BUTYL [(1R)-1-CYANO-2-PHENYLETHYL]CARBAMATE
• Synonyms: TERT-BUTYL [(1R)-1-CYANO-2-PHENYLETHYL]CARBAMATE
• CAS NO: 400652-45-1
• Molecular Formula: C₁₄H₁₈N₂O₂
• Molecular Weight: 246.30492
• Mol File: 400652-45-1.mol
• Article Data: 8

Chemical Properties

• Appearance: /
• CAS DataBase Reference: TERT-BUTYL [(1R)-1-CYANO-2-PHENYLETHYL]CARBAMATE(CAS DataBase Reference)
• NIST Chemistry Reference: TERT-BUTYL [(1R)-1-CYANO-2-PHENYLETHYL]CARBAMATE(400652-45-1)
• EPA Substance Registry System: TERT-BUTYL [(1R)-1-CYANO-2-PHENYLETHYL]CARBAMATE(400652-45-1)

Safety Data

• Hazardous Substances Data: 400652-45-1(Hazardous Substances Data)

Usage

General Description

Tert-butyl [(1R)-1-cyano-2-phenylethyl]carbamate is a chemical compound with the molecular formula C15H22N2O2. It is a carbamate derivative that is commonly used in organic synthesis and as a protecting group in peptide chemistry. TERT-BUTYL [(1R)-1-CYANO-2-PHENYLETHYL]CARBAMATE is a colorless solid that is soluble in organic solvents such as ethanol and acetone. It is also known for its potential biological activity and has been studied as a potential drug candidate for various therapeutic applications. Additionally, it is an important intermediate in the synthesis of pharmaceuticals and agrochemicals, making it a valuable compound in the field of chemical research and development.

Upstream product

• 129095-62-1 (R)-tert-butyl (1-amino-1-oxo-3-phenylpropan-2-yl)carbamate 
• 914955-62-7 [1-(4-methylbenzenesulfonyl)-2-phenylethyl]carbamic acid tert-butyl ester 
• 75-86-5 2-hydroxy-2-methylpropanenitrile 
• 77119-85-8 N-(tert-butoxycarbonyl)-D-phenylalaninal 
• 1033194-57-8 N-Boc D-E/Z-phenylalaninal oxime 
• 13033-84-6 D-phenylalanine methyl ester hydrochloride 
• 19901-50-9 methyl (2R)-2-(t-butoxycarbonylamino)-3-phenylpropionate 

Downstream Products

• 159517-27-8 (R)-2-amino-3-phenylpropanenitrile 

Relevant articles and documents

Optimization strategy of single-digit nanomolar cross-class inhibitors of mammalian and protozoa cysteine proteases

Cysteine proteases (CPs) are involved in a myriad of actions that include not only protein degradation, but also play an essential biological role in infectious and systemic diseases such as cancer. CPs also act as biomarkers and can be reached by active-

METHOD FOR PRODUCING CHIRAL AMINONITRILES

The invention relates to a method for preparing an N-acyl- or N-sulfonyl-α-aminonitrile, comprising the following steps: a) condensation of an N-acyl- or N-sulfonyl-α-aminoaldehyde with hydroxylamine to give an aldoxime, and b) dehydration of the aldoxime

One-pot conversion of aldehydes to nitriles mediated by TiCl4

A simple and convenient one-pot synthesis of nitriles from the corresponding aliphatic and aromatic aldehydes has been developed. The titanium tetrachloride assisted reaction was conducted in pyridine under mild conditions using various types of aldehyde precursors and gave the corresponding nitriles in excellent yields. The application of the adopted protocol to isolated aldoxime intermediates provided the corresponding nitriles with yields comparable to those using the one-pot procedure.