40076-71-9Relevant academic research and scientific papers
Synthesis and antimicrobial evaluation of novel platensimycin analogues
Plesch, Eva,Bracher, Franz,Krauss, Juergen
, p. 657 - 662 (2012/09/25)
Since the isolation of the natural products platensimycin and platencin as new antibiotic lead structures, several total syntheses as well as syntheses of derivatives have been developed. Most of these approaches are very laborious and the target molecule
6-Phenyl-6-alkylamido-5,6-dihydro-2H-pyran-2-ones: Novel HIV protease inhibitors
Hamilton, Harriet W.,Tait, Bradley D.,Gajda, Christopher,Hagen, Susan E.,Ferguson, Donna,Lunney, Elizabeth A.,Pavlovsky, Alexander,Tummino, Peter J.
, p. 719 - 724 (2007/10/03)
Publications from our laboratories have recently described a series of 3-thioaryl substituted-4-hydroxy-pyrones as HIV protease inhibitors. The current work examines the analogues 5,6-dihydro-2H-pyran-2-ones with 6,6-substitutions focusing on the use of 1
