40101-60-8

Upstream product

• 520-03-6 N-phenylphthalimide 
• 98-88-4 benzoyl chloride 
• 5383-83-5 4–(1,3-dioxoisoindolin-2-yl)benzoyl chloride 
• 71-43-2 benzene 
• 88-99-3 benzene-1,2-dicarboxylic acid 
• 62-53-3 aniline 
• 85-44-9 phthalic anhydride 
• 106075-25-6 p-phthalimidobenzoic acid azide 
• 615-42-9 1,2-Diiodobenzene 
• 201230-82-2 carbon monoxide 
• 1137-41-3 (4-aminophenyl)(phenyl)methanone 

Downstream Products

• 1137-41-3 (4-aminophenyl)(phenyl)methanone 
• 88-99-3 benzene-1,2-dicarboxylic acid 

Relevant academic research and scientific papers

A Bifunctional Iron Nanocomposite Catalyst for Efficient Oxidation of Alkenes to Ketones and 1,2-Diketones

We herein report the fabrication of a bifunctional iron nanocomposite catalyst, in which two catalytically active sites of Fe-Nx and Fe phosphate, as oxidation and Lewis acid sites, were simultaneously integrated into a hierarchical N,P-dual doped porous carbon. As a bifunctional catalyst, it exhibited high efficiency for direct oxidative cleavage of alkenes into ketones or their oxidation into 1,2-diketones with a broad substrate scope and high functional group tolerance using TBHP as the oxidant in water under mild reaction conditions. Furthermore, it could be easily recovered for successive recycling without appreciable loss of activity. Mechanistic studies disclose that the direct oxidation of alkenes proceeds via the formation of an epoxide as intermediate followed by either acid-catalyzed Meinwald rearrangement to give ketones with one carbon shorter or nucleophilic ring-opening to generate 1,2-diketones in a cascade manner. This study not only opens up a fancy pathway in the rational design of Fe-N-C catalysts but also offers a simple and efficient method for accessing industrially important ketones and 1,2-diketones from alkenes in a cost-effective and environmentally benign fashion.

High-triplet-level phthalimide based acceptors for exciplexes with multicolor emission

To provide high exciton utilization in organic light emitting diodes, phthalimide derivatives were designed and synthesized as exciplex-forming materials. Due to high triplet levels (2.92–3.11 eV) and ionization potentials (7.18–7.29 eV), the developed phthalimide derivatives were found to be not only appropriate accepting materials for the formation of different color exciplexes but also as bifunctional materials with a satisfactory hole and exciton-blocking abilities. Solid-state blends of the synthesized phthalimides as acceptors and a carbazole containing donors showed exciplex emission. Bimolecular blends exhibited multicolor exciplex emission which covered a visible spectrum from sky-blue to red colors, depending on the donor used. However, the photoluminescence quantum efficiencies of the studied exciplex-forming systems were found to be sensitive to the molecular design of the phthalimides. Acceptor with para-substituted phthalimide showed better exciplex-forming properties in comparison to other compounds. Exciplex-forming blend of (2-(4-benzoylphenyl)isoindoline-1,3-dione) as an acceptor and 1,3-di(9H-carbazol-9-yl)benzene (mCP) as a donor showed the most efficient sky-blue emission with small singlet-triplet splitting (0.06 ± 0.03eV). Such exciplex-forming molecular mixture was implemented as the light-emitting material in the sky-blue organic light emitting diodes which showed the brightness of 2500 cd m?2 and maximum external quantum efficiency of 2.9% due to the employment of both singlet and triplet excitons.

Preparation of N-Substituted Phthalimides by Palladium-Catalyzed Carbonylation and Coupling of o-Dihalo Aromatics and Primary Amines

A novel method for the formation of N-substituted phthalimides is described which is based on the palladium-catalyzed carbonylation and coupling of o-dihalo aromatics and primary amines.Optimal conditions established for the reaction using o-diiodobenzene and aniline were DMAc (0.2 M), 115 deg C, 90 psi of CO, 3 percent PdCl2L2, and 2.4 equiv of DBU.This process is tolerant of a wide variety of functional groups and gives good yields of the desired products.Variables such as temperature, catalyst type and loading, CO pressure, solvent, and base were examined to optimize this reaction.The reaction of aniline with 1,2-dibromocyclopentene under similar conditions gave a variety of products.

Acid Azides: Part X - New Synthesis and Decomposition Reactions of Phthalimidobenzoic Acid Azides

The o-, m-, and p-phthalimidobenzoic acid azides (IIa-c) have been synthesized via the reaction of the corresponding acid chlorides (Ia-c) with aq.NaN3 in acetone.The base-catalyzed decomposition of IIa-c with aromatic amines and/or hydrazines shows that

Hypolipidemic Activity of Phthalimide Derivatives. 2. N-Phenylphthalimide and Derivatives

A series of substituted N-phenylphthalimide derivatives was synthesized and examined for their ability to lower serum cholesterol and triglyceride levels in mice at 20 (mg/kg)/day, ip.Of the newly synthesized compounds, the most potent compound, o-(N-phthalimido)acetophenone, lowered serum cholesterol 57percent after 16 days and lowered serum triglyceride levels 44percent after 14 days. o-(N-Phthalimido)acetophenone was observed to be active in both normogenic (normal blood lipids levels) and hyperlipidemic mice and normogenic rats.In the latter, the reduction of serum lipids was reversible.The mode of action of this compound appeared to be multiple, including blockage of the de novo synthesis of lipids and acceleration of the excretion of lipids.The lipoprotein fractions of rat blood were reduced significantly in cholesterol, triglyceride, and neutral lipid content after 14 days treatment with o-(N-phthalimido)acetophenone.