40108-73-4

Usage

Uses

Used in Pharmaceutical Industry:
1,2,4-Triazin-6(1H)-one, 3-phenyl-5-(phenylmethyl)is used as a potential candidate for the development of new pharmaceutical drugs due to its biological and pharmacological activities, including its antiviral and antimicrobial properties.
Used in Agrochemical Industry:
1,2,4-Triazin-6(1H)-one, 3-phenyl-5-(phenylmethyl)is used as a potential candidate for the development of new agrochemicals, given its potential biological activities that may be beneficial in agricultural applications.

Upstream product

• 680-31-9 N,N,N,N,N,N-hexamethylphosphoric triamide 
• 17606-70-1 (4Z)-4-benzylidene-2-phenyl-1,3-oxazol-5(4H)-one 
• 1485432-34-5 C₆H₁₉N₄P*C₁₅H₁₀O₄ 
• 842-74-0 4-benzylidene-2-phenyloxazole-5(4H)-one 
• 130814-94-7 (Z)-N-(3-hydrazinyl-3-oxo-1-phenylprop-1-en-2-yl)benzamide 
• 40108-63-2 N-(3-hydrazinyl-3-oxo-1-phenylprop-1-en-2-yl)benzamide 
• 100-52-7 benzaldehyde 
• 1564-64-3 9-Bromoanthracene 
• 5122-94-1 4-biphenylboronic acid 
• 477552-78-6 2-phenyl-4-(phenylmethylene)-1,3-oxazolidin-5-one 

Downstream Products

• 127525-49-9 3-phenyl-5-benzyl-1,2,4-triazine-6(1H)-thione 
• 871250-95-2 5-benzyl-3-phenyl-1-(2,3,5-tri-O-benzoyl-β-D-ribofuranosyl)-1,2,4-triazin-6(1H)-thione 
• 227951-67-9 3,5-diphenyl-1-thia-4,6,7-triaza-indene 

Relevant academic research and scientific papers

Core-Modified Coelenterazine Luciferin Analogues: Synthesis and Chemiluminescence Properties

In this work on the design and studies of luciferins related to the blue-hued coelenterazine, the synthesis of heterocyclic analogues susceptible to produce a photon, possibly at a different wavelength, is undertaken. Here, the synthesis of O-acetylated derivatives of imidazo[1,2-b]pyridazin-3(5 H)-one, imidazo[2,1-f][1,2,4]triazin-7(1 H)-one, imidazo[1,2-a]pyridin-3-ol, imidazo[1,2-a]quinoxalin-1(5 H)-one, benzo[f]imidazo[1,2-a]quinoxalin-3(11 H)-one, imidazo[1′,2′:1,6]pyrazino[2,3-c]quinolin-3(11 H)-one, and 5,11-dihydro-3 H-chromeno[4,3-e]imidazo[1,2-a]pyrazin-3-one is described thanks to extensive use of the Buchwald–Hartwig N-arylation reaction. The acidic hydrolysis of these derivatives then gave solutions of the corresponding luciferin analogues, which were studied. Not too unexpectedly, even if these were “dressed” with substituents found in actual substrates of the nanoKAZ/NanoLuc luciferase, no bioluminescence was observed with these compounds. However, in a phosphate buffer, all produced a light signal, by chemiluminescence, with extensive variations in their respective intensity and this could be increased by adding a quaternary ammonium salt in the buffer. This aspect was actually instrumental to determine the emission spectra of many of these luciferin analogues.

Dianthracene compound containing pyridyl at tail end and application thereof

The invention provides dianthracene compounds shown in a general formula I in the specification. In the general formula I, L1 and L2 independently represent single bonds, substituted or unsubstituted heterocyclic aromatic groups of C2-C60 or substituted or unsubstituted hydrocarbon aromatic groups of C6-C60; L3 represents a substituted or unsubstituted heterocyclic aromatic group of C2-C60 or a substituted or unsubstituted hydrocarbon aromatic group of C6-C60; R10, R11, R12, R13, R14, R15, R16, R17, R18, R21, R23, R24, R25, R26, R27 and R28 independently represent hydrogen, halogen and substituted or unsubstituted alkyl or alkoxy of C1-C10. The compounds have good luminescence properties, high electron transport capacities and terrific solubility and can be used in luminescent materials, electron transport materials and hole-blocking materials in the electroluminescence field. The invention also provides an organic electroluminescence device at least comprising a pair of electrodes and organic luminescent media between the electrodes. The organic luminescent media at least comprise the dianthracene compounds.

Organic compound and electronic element and electronic device using same (by machine translation)

The invention belongs to the technical field of organic materials, and particularly relates to an organic compound and an electronic element and an electronic device using the same, wherein the organic compound has the structure shown 1. When the compound is used as an electron transport layer for preparing an organic electroluminescent device, the service life of the organic electroluminescent device can be effectively prolonged, and the luminous efficiency or the driving voltage can be improved to a certain extent. (by machine translation)

Blue light electroluminescent material and application thereof

The invention relates to a blue light electroluminescent material and an application thereof. A structural formula of the blue light electroluminescent material is represented by a chemical formula 1shown in the specification. The blue light electroluminescent material provided by the invention has the advantages of high luminous efficiency, high color saturation, good film-forming performance, better thermal stability and the like; compared with a conventional blue host material, the blue light electroluminescent material provided by the invention has the characteristics of high luminous efficiency and long service life of a prepared device; and inventors also find that when a deuterium element is introduced into the material structure, by using the characteristics of the deuterium element, the quantum efficiency, color saturation, service life and the like can be improved, and at the same time, the material has higher tolerance when used for preparing the device.

Electron transport material and synthesis method and application thereof

The invention relates to an electron transport material as well as a synthesis method and application thereof, and belongs to the technical field of preparation and application of organic photoelectric materials. The molecular structure of the electron transport material is shown as general formula I. The electron transport material with a novel structure provided by the invention can be used as an electron transport material of organic light-emitting devices to improve the light-emitting efficiency of the devices. The preparation method of the electron transport material provided by the invention has the advantages of simple synthesis process and high product purity.

COMPOUND FOR ORGANIC ELECTROLUMINESCENT ELEMENT AND ORGANIC ELECTROLUMINESCENT ELEMENT USING THE SAME

PROBLEM TO BE SOLVED: To provide a compound for an organic electroluminescent element which allows a sufficiently long driving life to be obtained when used as a constituent material of an organic electroluminescent element, and to provide an organic electroluminescent element using the compound. SOLUTION: The compound for an organic electroluminescent element is an anthracene compound having at least one substituent represented by general formula (2). The organic electroluminescent element uses the compound. (L is a linking group and is a single bond, a substituted/unsubstituted arylene group, a substituted/unsubstituted divalent group having a heterocyclic skeleton, or the like; and R1 and R2 are each independently H, a substituted/unsubstituted alkyl group, or the like.) SELECTED DRAWING: None COPYRIGHT: (C)2016,JPOandINPIT

NEW NITROGEN-CONTAINING HETEROCYCLIC COMPOUNDS AND ORGANIC ELECTRONIC DEVICE USING THE SAME

The present invention refers to novel nitrogenous heterocyclic and optical material using it organic electronic device with high. The present invention according to organic electronic devices efficiency, excellent characteristics such as voltage and life blades, presenting a. (by machine translation)

Utility of 4-Benzylidene-2-phenyl-5(4H)-oxazolone in Synthesis of Triazine, Oxadiazole and Imidazole Derivatives of Anticipated Biological Activity

Treatment of oxazolone 1 with hydrazine hydrate at room temperature gave the (Z)-configurated isomer hydrazide (Z)-3 (high yield). However, refluxing 1 with hydrazine hydrate yielded the (E)-configurated isomer hydrazide (E)-2 (low yield).The hydrazide derivative (Z)-3 has been utilized as synthon for the synthesis of 1,2,4-triazinone, imidazolone, and oxadiazole derivatives through appropriate routes. The thiosemicarbazide and semicarbazide derivatives are synthesized by different routes. The structures of the new compounds were established on the basis of IR, 1H-NMR, mass spectral data, and elemental analysis.

Design, synthesis, and biological evaluation of hydrazone incorporated 1,2,4-triazines as anticonvulsant agents

New hydrazone incorporated triazines were designed and synthesized using an appropriate synthetic route with regard to essential pharmacophores, and evaluated for their anticonvulsant activity through maximal electroshock seizure (MES) and subcutaneous pentylenetetrazole-induced seizure (scPTZ) screenings. Among the tested compounds, 4-[{2-(5-(3-chlorobenzyl)-3-phenyl-1,2,4-triazine-6-yl)hydrazono} methyl]-N,N-dimethylaniline 6k (MES ED50 54.31, scPTZ ED50 92.01) and 4-[{2-(5-(4-chlorobenzyl)-3-phenyl-1,2,4-triazine-6-yl)hydrazono}methyl]-N,N-dimethylaniline 6r (MES ED50 46.05, scPTZ ED50 83.90) emerged as the most active anticonvulsant agents having GABAergic effects. Compounds 6k and 6r also showed lesser CNS depressant effect than the standard drug carbamazepine. To obtain further insights into the binding interactions of these molecules, molecular docking studies were carried out.

Application to photoreactive materials of photochemical generation of superbases with high efficiency based on photodecarboxylation reactions

A thin film of polystyrene containing 4c was spin-coated on a CaF2 plate and irradiated with 365 nm light. The absorption band arising from the carboxylate of 4c at 1372 cm-1 in the FTIR spectrum decreased after UV irradiation. Radical UV curing materials that are well established in the marketplace have drawbacks because of high volume shrinkage and oxygen inhibition. The anionically cured film showed high transparency and no volume shrinkage, in contrast to a conventional radical UV curing system, which showed large volume shrinkage. This is probably due to relatively low quantum yields for photobase generation and weaker basicity of photo-generated bases, leading to low photosensitivity of photoreactive materials sensitized with photobase generators. Furthermore, many of the photobase generators reported are generally prepared via several synthetic steps.