40113-63-1

Upstream product

• 17112-11-7 p-toluidine (protonated) 
• 67-56-1 methanol 
• 88-05-1 2,4,6-trimethylaniline 
• 603-71-4 nitromesitylene 
• 3095-38-3 3,5-dimethyl-4-nitrobenzoic acid 
• 18515-22-5 (3,5-dimethyl-4-nitrophenyl)methanol 
• 24992-34-5 2,4,6-trimethyl-aniline; protonated form 
• 124-41-4 sodium methylate 
• 89210-26-4 4-(hydroxymethyl)-2,6-dimethylbenzenamine 
• 40113-64-2 4-(methoxymethyl)-2,6-dimethylnitrobenzene 

Downstream Products

• 40113-57-3 2,6-dimethyl-3-(methoxymethyl)-p-benzoquinone 4-(2,4,6-trimethylanil) 
• 1139569-15-5 2-isocyanato-1,3-dimethyl-5-[(methyloxy)methyl]benzene 
• 40113-58-4 2,6-dimethyl-3-(methoxymethyl)-p-benzoquinone 

Relevant academic research and scientific papers

GLYCOGEN PHOSPHORYLASE INHIBITOR COMPOUND AND PHARMACEUTICAL COMPOSITION THEREOF

This invention relates to a novel compound which is a glycogen phosphorylase inhibitor and its use in the treatment of diabetes and other conditions associated therewith. The invention further relates to a pharmaceutical composition containing the compoun

Oxidation of Aromatic Compounds. I. Oxidation of Methyl Derivatives of Nitrobenzene and Aniline in the System HSO3F-PbO2

Low-temperature oxidation of methyl derivatives of nitrobenzene and aniline in the system HSO3F-PbO2 proceeds with intermediate formation of radical cations and results in replacement of hydrogen in one or two methyl groups or yields compounds of the diphenylmethane and biphenyl series.

THE ESR SPECTRA, STRUCTURE, AND REACTIVITY OF AROMATIC RADICAL-CATIONS IN SUPERACIDS

The oxidation of aromatic compounds by lead dioxide in superacids based on fluorosulfonic acid at -75 deg C takes place by a one-electron mechanism and leads in many cases to relatively stable radical-cations.The ESR spectra, the isotropic hyperfine coupling constants, data on the reactivity of the radical-cations, and the structures of the final products from their transformations under "long-life" conditions are presented.

Migrations in Oxidations of Mesidine

The oxidation of mesidine in methanolic media by ferricyanide, dichromate, and persulfate afforded an anil 4 containing a shifted methoxymethyl group in addition to the principal anil 3 formed by oxidative dealkylation.Possible intermediates 6, 7, and 8 were prepared and oxidized to the product anils.Oxidations of related anilines 9, 10, and 13 did not parallel those of mesidine but afforded analogues of 3.There is significant spectral evidence for anils with alkyl shifts but little for anils analogous to 4.