402-17-5

Basic information

• Product Name: 2-NITRO-5-(TRIFLUOROMETHYL)PHENOL
• Synonyms: 2-NITRO-5-(TRIFLUOROMETHYL)PHENOL;2-Nitro-5-(trifluoromethyl)phenol, 2-Hydroxy-4-(trifluoromethyl)nitrobenzene;3-Hydroxy-4-nitrobenzotrifluoride;2-Nitro-5-(trifluoromethyl)phenol, 2-Hydroxy-4-(trifluoromethyl)nitrobenzene, 6-Nitro-alpha,alpha,alpha-trifluoro-m-cresol;Phenol, 2-nitro-5-(trifluoromethyl)-;2-Nitro-5-(trifluoromethyl)
• CAS NO: 402-17-5
• Molecular Formula: C₇H₄F₃NO₃
• Molecular Weight: 207.11
• EINECS: 200-528-9
• Mol File: 402-17-5.mol
• Article Data: 19

Chemical Properties

• Boiling Point: 108-111°@34mm°
• Flash Point: 98.559 °C
• Appearance: /
• Density: 1.555 g/cm³
• Vapor Pressure: 0.026mmHg at 25°C
• Refractive Index: 1.507
• Storage Temp.: Inert atmosphere,Room Temperature
• PKA: 5.83±0.13(Predicted)
• CAS DataBase Reference: 2-NITRO-5-(TRIFLUOROMETHYL)PHENOL(CAS DataBase Reference)
• NIST Chemistry Reference: 2-NITRO-5-(TRIFLUOROMETHYL)PHENOL(402-17-5)
• EPA Substance Registry System: 2-NITRO-5-(TRIFLUOROMETHYL)PHENOL(402-17-5)

Safety Data

• HazardClass: IRRITANT
• Hazardous Substances Data: 402-17-5(Hazardous Substances Data)

Usage

General Description

2-Nitro-5-(trifluoromethyl)phenol is a compound with the chemical formula C7H4F3NO3. It is a nitrophenol derivative with a trifluoromethyl group attached to the phenol ring. This chemical is commonly used as an intermediate or raw material in the synthesis of various pharmaceuticals, agrochemicals, and dyes. It is also used as a stabilizer in organic solvents and as an intermediate in the manufacturing of fragrances and other chemicals. Additionally, 2-Nitro-5-(trifluoromethyl)phenol has been studied for its potential antimicrobial and antioxidant properties. Overall, this compound has important industrial applications and potential for further research in various fields.

InChI:InChI=1/C7H4F3NO3/c8-7(9,10)4-1-2-5(11(13)14)6(12)3-4/h1-3,12H

Upstream product

• 402-11-9 3-chloro-4-nitrobenzotrifluoride 
• 98-17-9 3-Trifluoromethylphenol 
• 402-54-0 p-nitrobenzotrifluoride 
• 402-14-2 2-nitro-5-(trifluoromethyl)aniline 

Downstream Products

• 907587-46-6 methyl 4-[(2-nitro-5-(trifluoromethyl)phenoxy)methyl]benzoate 
• 914636-97-8 2-methoxy-1-nitro-4-(trifluoromethyl)benzene 
• 1413929-93-7 C₁₅H₁₁ClF₃NO₂S 
• 1413930-09-2 C₁₅H₉ClF₃NO₂ 
• 1413929-86-8 C₁₅H₁₁ClF₃NO₂S 
• 1413930-03-6 C₁₅H₉ClF₃NO₂ 
• 609850-66-0 C₂₃H₂₂F₇NO₂ 
• 343340-72-7 2-amino-5-trifluoromethyl-phenol hydrochloride 
• 442-79-5 4-nitro-benzoic acid-(6-trifluoromethyl-[8]quinolyl ester) 
• 391-49-1 toluene-4-sulfonic acid-(6-trifluoromethyl-[8]quinolyl ester) 
• 90800-42-3 8-hydroxy-quinoline-6-carboxylic acid 
• 321-70-0 6-trifluoromethyl-quinolin-8-ol 
• 209686-79-3 methyl 4-{[2-[(cyclopentylmethyl)(phenylsulfonyl)amino]-5-(trifluoromethyl)phenoxy]methyl}benzoate 
• 907587-59-1 methyl 4-{[2-[neopentyl(phenylsulfonyl)amino]-5-(trifluoromethyl)phenoxy]methyl}benzoate 

Relevant articles and documents

Vapochromic Luminescent π-Conjugated Systems with Reversible Coordination-Number Control of Hypervalent Tin(IV)-Fused Azobenzene Complexes

The dynamic and reversible changes of coordination numbers between five and six in solution and solid states, based on hypervalent tin(IV)-fused azobenzene (TAz) complexes, are reported. It was found that the TAz complexes showed deep-red emission owing t

Synthesis and in vitro antimycobacterial and isocitrate lyase inhibition properties of novel 2-methoxy-2′-hydroxybenzanilides, their thioxo analogues and benzoxazoles

A new series of 2-methoxy-2′-hydroxybenzanilide derivatives and their thioxo analogues have been synthesised and characterised by IR, NMR and elemental analysis. These compounds were investigated for their in vitro antimycobacterial activities against Mycobacterium tuberculosis 331/88, Mycobacterium avium 330/88, Mycobacterium kansasii 235/80, clinically isolated M. kansasii 6509/96 and the ability to act as in vitro isocitrate lyase inhibitors. The best ICL inhibitors were two compounds from the thiobenzanilide group (8f, 8m), which exhibited an inhibition potential that was equal to the standard compound, 3-nitropropionic acid. In addition, the best antimycobacterial properties were exhibited by benzanilide derivatives 6h, 6k and 6l with 5-Cl and 4′ or 5′ Cl/Br substitution. For all the thiobenzanilide derivatives tested, two conformers were observed in the NMR spectra, which is most likely due to the hindered rotation of the C-N bond.

HARMFUL ARTHROPOD CONTROL COMPOSITION, AND FUSED HETEROCYCLIC COMPOUND

Disclosed is a harmful arthropod control composition comprising, as an active ingredient, a fused heterocyclic compound represented by formula (1) [wherein A1 and A2 independently represent a nitrogen atom or the like; R1 and R4 independently represent a halogen atom or the like; R2 and R3 independently represent a halogen atom or the like; R5 and R6 independently represent a linear C1-C6 hydrocarbon group which may be substituted, or the like (provided that both R5 and R6 cannot represent a hydrogen atom simultaneously); and n represents 0 or 1]. The harmful arthropod control composition has an excellent efficacy to control harmful arthropods.