4024-28-6 Usage
Heterocyclic Compound
Contains an imidazole ring fused to a quinoline ring.
Derivative
Derived from imidazoquinolinone.
Utility
Commonly utilized in pharmaceutical research and drug development.
Biological Activities
Antiviral: Exhibits potential in combating viral infections.
Anticancer: Shows promise in cancer treatment.
Anti-inflammatory: Demonstrates anti-inflammatory properties.
Ongoing Research
Continual investigation into its exact biological and pharmacological properties.
Interest in Medicinal Chemistry
Attracts attention for its distinctive structure and potential medicinal benefits.
Check Digit Verification of cas no
The CAS Registry Mumber 4024-28-6 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 4,0,2 and 4 respectively; the second part has 2 digits, 2 and 8 respectively.
Calculate Digit Verification of CAS Registry Number 4024-28:
(6*4)+(5*0)+(4*2)+(3*4)+(2*2)+(1*8)=56
56 % 10 = 6
So 4024-28-6 is a valid CAS Registry Number.
4024-28-6Relevant academic research and scientific papers
Directed C(sp3)-H arylation of tryptophan: Transformation of the directing group into an activated amide
Nicke, Lennart,Horx, Philip,Harms, Klaus,Geyer, Armin
, p. 8634 - 8641 (2019/10/01)
The 8-aminoquinoline (8AQ) directed C(sp3)-H functionalization was applied in the synthesis of β-arylated tryptophan derivatives. The laborious protecting group reorganization towards α-amino acids compatible for solid phase peptide synthesis (SPPS) was cut short by the transformation of the directing group into an activated amide, which was either used directly in peptide coupling or in the gram scale synthesis of storable Fmoc-protected amino acids for SPPS. In this work, directed C-H activation and nonplanar amide chemistry complement each other for the synthesis of hybrids between phenylalanine and tryptophan with restricted side chain mobility.
