40248-01-9

Upstream product

• 108-73-6 3,5-dihydroxyphenol 
• 74-89-5 methylamine 
• 1027267-53-3 (3,5-Dimethoxy-phenyl)-methyl-carbamic acid tert-butyl ester 
• 384793-29-7 (3,5-dimethoxyphenyl)-carbamic acid tert-butyl ester 
• 10272-07-8 3.5-dimethoxyaniline 

Downstream Products

• 1025887-82-4 N-methyl-3,5-bis(tert-butyldimethylsilyloxy)aniline 

Relevant academic research and scientific papers

Synthesis and protein tyrosine phosphatase inhibitory activity of dephostatin analogs

We have synthesized derivatives of dephostatin, a protein tyrosine phosphatase (PTPase) inhibitor, to study the structure-activity relationships of this inhibitor. Inactive analogs revealed some insight into structural requirements for PTPase inhibitory activity of dephostatin. Both a nitroso group and phenolic hydroxyl groups were found to be essential for the inhibitory activity. Among the dephostatin derivatives synthesized, one of the regioisomers of dephostatin showed PTPase inhibitory activity equivalent to that of dephostatin, and also had increased stability.

Cyclohexanediones and their use as plant growth regulators

The invention relates to the novel cyclohexanediones of formula I STR1 in which R is hydrogen or C1 -C6 -alkyl, A is R2, OR3 or NR3 R4, R2 is C1 -C6 -alkyl that is unsubstituted or is mono-substituted by C1 -C4 -alkoxy or mono- or poly-substituted by halogen, or is C3 -C6 -cycloalkyl, R3 is C1 -C6 -alkyl or C3 -C6 -cycloalkyl, or is phenyl or benzyl each of which is unsubstituted or is mono-, di- or tri-substituted by R5, R4 is hydrogen, C1 -C6 -alkyl, C1 -C4 -alkoxy or C3 -C6 -cycloalkyl, R3 and R4 are, in addition, together with the nitrogen atom to which they are bonded, a pyrrolidine, morpholine or piperidine radical, B is one of the radicals STR2 m is 0, 1, 2 or 3, R5 is halogen, nitro, cyano, C1 -C4 -alkyl, C1 -C4 -alkoxy, C1 -C4 -alkylthio, C1 -C4 -haloalkyl, C1 -C4 -alkylsulphinyl or C1 -C4 -alkylsulphonyl, R6 is C1 -C6 -alkyl or C3 -C6 -cycloalkyl, and R7 is hydrogen, C1 -C6 -alkyl, C1 -C6 -haloalkyl, C3 -C6 -alkenyl, C3 -C6 -haloalkenyl or C3 -C6 -alkynyl, and to salts of the compounds of formula I with acids, bases or complex-formers, to processes for the preparation thereof and to novel intermediates. The compounds of formula I have herbicidal and growth-regulating action.