402925-25-1Relevant articles and documents
Potent, selective inhibitors of protein tyrosine phosphatase 1B
Xin, Zhili,Oost, Thorsten K.,Abad-Zapatero, Cele,Hajduk, Philip J.,Pei, Zhonghua,Szczepankiewicz, Bruce G.,Hutchins, Charles W.,Ballaron, Steve J.,Stashko, Mike A.,Lubben, Tom,Trevillyan, James M.,Jirousek, Mike R.,Liu, Gang
, p. 1887 - 1890 (2007/10/03)
We have previously reported a novel series of oxalyl-aryl-amino benzoic acid-based, catalytic site-directed, competitive, reversible protein tyrosine phosphatase 1B (PTP1B) inhibitors. With readily access to key intermediates, we utilized a solution phase