40356-35-2Relevant articles and documents
Synthesis and conformational characterization of diketopiperazines bearing a benzyl moiety
Nakao, Michiyasu,Toriuchi, Yuriko,Fukayama, Shintaro,Sano, Shigeki
, p. 340 - 342 (2014/03/21)
Diketopiperazines bearing a benzyl moiety with different para-substituents were synthesized and analyzed by 1HNMR spectroscopy. All of these diketopiperazines were found to adopt a folded conformation according to the upfield chemical shift of the cis-proton (cis to the benzyl moiety) due to a shielding effect in the 1HNMR spectra. An intramolecular CH-π interaction appears to be an important factor for the folded conformation due to the effects of para-substituents on the benzyl group.
A new coupling reagent for peptide synthesis. Benzotriazolvyloxy-bis (pyrroltdino) -carbonium hexaflouorophosphate (BBC)
Chen, Shaoqing,Xu, Jiecheng
, p. 647 - 650 (2007/10/02)
Benzotriazolyloxy-bis(pyrrolidino)-carbonium hexa- fluorophosphate (BBC) is found to be a new excellent coupling reagent devoid of cytotoxic by-product instead of HBTU and BOP. It has been applied in the solution and solid phase peptide synthesis.
PENTAFLUOROPHENYL DIPHENYLPHOSPHINATE A NEW EFFICIENT COUPLING REAGENT IN PEPTIDE CHEMISTRY
Chen, Shaoqing,Xu, Jiecheng
, p. 6711 - 6714 (2007/10/02)
Pentafluorophenyl diphenylphosphinate was found to be a new efficient coupling reagent for the racemization-free synthesis of peptides.It has been applied in both the solution and the solid phase peptide synthesis.