403642-45-5Relevant academic research and scientific papers
Selective functionalization in positions 2 and 3 of indole via an iodine - Copper exchange reaction
Yang, Xiaoyin,Althammer, Andreas,Knochel, Paul
, p. 1665 - 1667 (2007/10/03)
Two selectively successive I/Cu exchange reactions performed with (Nphyl)CuLi allow the functionalization of indoles in positions 2 and 3. The 2,3-diketones prepared by this method can readily be converted to tricyclic heterocycles by standard methods.
Synthesis of β-carbolines from 2-Acyl-1-benzenesulfonyl-3-iodo-1H-indoles
Abbiati,Beccalli,Marchesini,Rossi
, p. 2477 - 2483 (2007/10/03)
2-Acyl-1-benzenesulfonyl-3-iodo-1H-indoles and 1-benzenesulfonyl-3-iodo-1H-indole-2-carbaldehyde give in satisfactory yields 1,3- and 3-substituted-β-carbolines, respectively, by combined palladium-catalyzed coupling with alk-1-ynes followed by 6-endo-dig
