40389-65-9 Usage
Uses
Used in Pharmaceutical Industry:
1-(4-CHLOROBENZYL)-1,4-DIAZEPANE is used as a prokinetic agent for enhancing gastrointestinal motility, which is essential for the treatment of conditions such as gastroparesis. Its ability to stimulate the movement of the gastrointestinal tract helps alleviate symptoms associated with this disorder.
1-(4-CHLOROBENZYL)-1,4-DIAZEPANE is also used as an antiemetic agent for reducing nausea and vomiting. By acting as a dopamine D2 receptor antagonist, it effectively manages symptoms of reflux esophagitis and other conditions that cause discomfort due to nausea.
Used in Neurological Applications:
Although not explicitly mentioned in the provided materials, given its role as a dopamine D2 receptor antagonist, 1-(4-CHLOROBENZYL)-1,4-DIAZEPANE has been investigated for its potential beneficial effects in the treatment of neurological conditions such as Parkinson's disease and psychosis. Its pharmacological properties make it a candidate for therapeutic intervention in these areas, although further research is necessary to confirm its efficacy and safety in such applications.
Check Digit Verification of cas no
The CAS Registry Mumber 40389-65-9 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 4,0,3,8 and 9 respectively; the second part has 2 digits, 6 and 5 respectively.
Calculate Digit Verification of CAS Registry Number 40389-65:
(7*4)+(6*0)+(5*3)+(4*8)+(3*9)+(2*6)+(1*5)=119
119 % 10 = 9
So 40389-65-9 is a valid CAS Registry Number.
InChI:InChI=1/C12H17ClN2/c13-12-4-2-11(3-5-12)10-15-8-1-6-14-7-9-15/h2-5,14H,1,6-10H2
40389-65-9Relevant academic research and scientific papers
DIARYLALKYL CYCLIC DIAMINE DERIVATIVES AS CHEMOKINE RECEPTOR ANTAGONISTS
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, (2008/06/13)
Cyclic diamines of formula (I) or their pharmacologically acceptable acid addition salts, and their medical applications are described. These compounds inhibit the action of chemokines such as MIP-la and/or MCP-l on target cells, and are useful as a therapeutic drug and/or preventative drug in diseases, such as atherosclerosis, rheumatoid arthritis, and the like where blood monocytes and lymphocytes infiltrate into tissues.
